Department of Oral and Maxillofacial Surgery, Federal Armed Forces Hospital, Rübenacherstr. 170, 56072 Koblenz, Germany.
Department of Oral and Maxillofacial Surgery-Plastic Operations, University Medical Center Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Medicina (Kaunas). 2021 Sep 14;57(9):965. doi: 10.3390/medicina57090965.
Oral mucosal melanoma (OMM) represents an extremely rare entity that is associated with a poor prognosis due to late diagnosis and early metastasis. Here, extensive surgical therapy is the therapy of choice. In contrary, for OMM in situ, the respective therapeutical recommendations are lacking. In this case report, treatment modalities of an OMM in situ of the palate, including the maxillary alveolar process, are reported. The tumor relapsed twice despite adequate surgical therapy and reconstruction. Therefore, irradiation was performed as an adjuvant therapy. At a follow-up of two years, the patient was free from recurrences.
口腔黏膜黑色素瘤（OMM）极为罕见，由于诊断较晚和早期转移，预后不良。在此，广泛的手术治疗是首选的治疗方法。相反，对于原位 OMM，缺乏相应的治疗建议。在本病例报告中，报告了一例累及腭部和上颌牙槽突的原位 OMM 的治疗方法。尽管进行了充分的手术治疗和重建，肿瘤仍复发了两次。因此，进行了放疗作为辅助治疗。随访两年后，患者无复发。
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