Symvoulakis Emmanouil K, Kyrmizakis Dionysios E, Drivas Emmanouil I, Koutsopoulos Anastassios V, Malandrakis Stylianos G, Skoulakis Charalambos E, Bizakis John G
Department of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece.
Head Face Med. 2006 Mar 28;2:7. doi: 10.1186/1746-160X-2-7.
Oral mucosal melanomas are highly malignant tumors. The 'chameleonic' presentation of a mainly asymptomatic condition, the rarity of these lesions, the poor prognosis and the necessity of a highly specialized treatment are factors that should be seriously considered by the involved health provider. We present the case of a 75-year-old man who was referred to the Ear, Nose and Throat department. His symptoms were voice alteration and saliva drooling, progressively worsening during the last few weeks. The absence of pain was the reason for the delay of seeking medical care. The diagnosis was an oversized oral melanoma. This is an example of how the time of diagnosis and the evolution of a disease could be seriously influenced by patient's behavior. Melanomas arising from oral mucosa have poor prognosis unless they are discovered and treated early. The vigilance of the physicians is necessary to have success in this difficult task.
口腔黏膜黑色素瘤是高度恶性肿瘤。其主要表现为无症状状态,这种“变色龙般”的表现、此类病变的罕见性、预后不良以及高度专业化治疗的必要性,都是相关医疗服务提供者应认真考虑的因素。我们报告一例75岁男性患者,他被转诊至耳鼻喉科。他的症状是声音改变和流口水,在过去几周内逐渐加重。无疼痛是他延迟就医的原因。诊断为巨大口腔黑色素瘤。这是一个例子,说明患者的行为如何严重影响疾病的诊断时间和病情发展。除非早期发现并治疗,口腔黏膜产生的黑色素瘤预后很差。医生保持警惕对于完成这项艰巨任务取得成功至关重要。