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经直接硬化疗法治疗的门静脉高压患者顽固性造口旁出血:一例报告

Intractable parastomal bleeding in a portal hypertensive patient managed by direct sclerotherapy: a case report.

作者信息

Ayoobi Yazdi Niloofar, Aletaha Najmeh, Mehrabinejad Mohammad-Mehdi, Zare Dehnavi Ali, Rokni Yazdi Hadi

机构信息

Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center(ADIR), Tehran University of Medical Sciences, Tehran, Iran.

Department of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Gastroenterol Hepatol Bed Bench. 2020 Winter;13(1):90-94.

Abstract

Patients with a stoma have 5% chance of developing parastomal varices, which tend to repetitive massive and life-threatening hemorrhages. Treatment of choice in parastomal varices have not been established, while Transjugular Intrahepatic Portosystemic Shunt (TIPS) has been revealed as the most successful measure. We report a hemodynamically unstable patient with a history of Ulcerative Colitis (UC) and Primary Sclerosing Cholangitis (PSC) with colostomy, because of colon cancer who presented with massive parastomal bleeding. Non-operative treatments and TIPS failed to control the symptoms. Color Doppler ultrasound showed a hepato-fugal flow. The direct antegrade technique, using Sodium Tetradecyl Sulfate (STS 1%) and glue-Lipiodol, was applied under ultrasonography guidance, and complete stoppage of bleeding was achieved. No immediate or late complication or follow-up recurrence were noted after 8 months. In case of hepatofugal flow, direct percutaneous mesenteric parastomal venous access and sclerotherapy is a rapid and relatively safe procedure for parastomal variceal bleeding.

摘要

有造口的患者发生造口旁静脉曲张的几率为5%,这种情况往往会反复出现大量出血并危及生命。目前尚未确定造口旁静脉曲张的首选治疗方法,而经颈静脉肝内门体分流术(TIPS)已被证明是最成功的治疗措施。我们报告了一名血流动力学不稳定的患者,该患者有溃疡性结肠炎(UC)和原发性硬化性胆管炎(PSC)病史,因结肠癌行结肠造口术,出现大量造口旁出血。非手术治疗和TIPS均未能控制症状。彩色多普勒超声显示肝外血流。在超声引导下采用直接顺行技术,使用十四烷基硫酸钠(1% STS)和胶水-碘油,成功实现了出血完全停止。8个月后未发现近期或远期并发症或随访复发情况。对于肝外血流的情况,直接经皮肠系膜造口旁静脉穿刺硬化治疗是一种治疗造口旁静脉曲张出血快速且相对安全的方法。

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