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评价 38mm 长度支架在长病变中的机械性能。

Evaluation of Mechanical Performances of Stents with 38 mm Length in Long Lesion.

机构信息

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

Henan Province Key Laboratory of Cardiac Injury and Repair, Zhengzhou, Henan 450052, China.

出版信息

Biomed Res Int. 2020 Feb 27;2020:2594161. doi: 10.1155/2020/2594161. eCollection 2020.

Abstract

OBJECTIVE

Single stent with 38 mm length has emerged as a potential solution for long lesion treatment using PCI. However, long stents need to come over a longer lesion length combined with a higher incidence of tortuous calcification, requiring a stent to provide superior transport and compliance and reduce elastic retraction. Here, we evaluated the mechanical performances of the existing four types of drug eluting stents with 38 mm length, which could provide guidance for clinicians to choose the proper stents for the patients.

METHODS

The stents with 38 mm length from XIENCE Xpedition (Abbott, US), SYNERGY (Boston Scientific, US), FIREHAWK (Microport, China), and HELIOS (HELIOS, China) were collected. Mechanical parameters of stents including crossing ability, compliance, elastic recoil, and longitudinal strength were performed.

RESULTS

The resistance force of stents from XIENCE Xpedition was smaller than FIREHAWK ( < 0.05), which indicates that the stent from XIENCE Xpedition has better crossing ability. The ratio of stent diameter reduction from both XIENCE Xpedition and SYNERGY was less than 3% with no statistical difference. In addition, the elastic recoil percentage of stents from SYNERGY, XIENCE Xpedition, FIREHAWK, and HELIOS was 1.16%, 2.62%, 3.66%, and 4.19%, respectively, indicating that SYNERGY had better elastic recoil compared to FIREHAWK and HELIOS ( < 0.05), which indicates that the stent from XIENCE Xpedition has better crossing ability. The ratio of stent diameter reduction from both XIENCE Xpedition and SYNERGY was less than 3% with no statistical difference. In addition, the elastic recoil percentage of stents from SYNERGY, XIENCE Xpedition, FIREHAWK, and HELIOS was 1.16%, 2.62%, 3.66%, and 4.19%, respectively, indicating that SYNERGY had better elastic recoil compared to FIREHAWK and HELIOS ( < 0.05), which indicates that the stent from XIENCE Xpedition has better crossing ability. The ratio of stent diameter reduction from both XIENCE Xpedition and SYNERGY was less than 3% with no statistical difference. In addition, the elastic recoil percentage of stents from SYNERGY, XIENCE Xpedition, FIREHAWK, and HELIOS was 1.16%, 2.62%, 3.66%, and 4.19%, respectively, indicating that SYNERGY had better elastic recoil compared to FIREHAWK and HELIOS (.

CONCLUSION

The evaluation of mechanical properties for the stent with 38 mm length including crossing ability, compliance, elastic recoil, and longitudinal strength could provide reference index for more accurately clinical application for long lesion treatment.

摘要

目的

长度为 38mm 的单支架已成为 PCI 治疗长病变的潜在解决方案。然而,长支架需要跨越更长的病变长度,并伴有更高的迂曲钙化发生率,这需要支架提供更好的输送性和顺应性,并减少弹性回缩。在这里,我们评估了四种现有长度为 38mm 的药物洗脱支架的机械性能,这可为临床医生为患者选择合适的支架提供指导。

方法

收集了雅培公司的 XIENCE Xpedition、波士顿科学公司的 SYNERGY、微创公司的 FIREHAWK 和 HELIOS 公司的 HELIOS 四种长度为 38mm 的支架。对支架的机械性能,包括通过能力、顺应性、弹性回缩和纵向强度进行了评估。

结果

与 FIREHAWK 相比,XIENCE Xpedition 支架的阻力更小( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。XIENCE Xpedition 和 SYNERGY 的支架直径减小比例均小于 3%,无统计学差异。此外,SYNERGY、XIENCE Xpedition、FIREHAWK 和 HELIOS 支架的弹性回缩百分比分别为 1.16%、2.62%、3.66%和 4.19%,表明 SYNERGY 的弹性回缩优于 FIREHAWK 和 HELIOS( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。与 FIREHAWK 相比,XIENCE Xpedition 支架的阻力更小( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。XIENCE Xpedition 和 SYNERGY 的支架直径减小比例均小于 3%,无统计学差异。此外,SYNERGY、XIENCE Xpedition、FIREHAWK 和 HELIOS 支架的弹性回缩百分比分别为 1.16%、2.62%、3.66%和 4.19%,表明 SYNERGY 的弹性回缩优于 FIREHAWK 和 HELIOS( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。与 FIREHAWK 相比,XIENCE Xpedition 支架的阻力更小( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。XIENCE Xpedition 和 SYNERGY 的支架直径减小比例均小于 3%,无统计学差异。此外,SYNERGY、XIENCE Xpedition、FIREHAWK 和 HELIOS 支架的弹性回缩百分比分别为 1.16%、2.62%、3.66%和 4.19%,表明 SYNERGY 的弹性回缩优于 FIREHAWK 和 HELIOS( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。与 FIREHAWK 相比,XIENCE Xpedition 支架的阻力更小( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。XIENCE Xpedition 和 SYNERGY 的支架直径减小比例均小于 3%,无统计学差异。此外,SYNERGY、XIENCE Xpedition、FIREHAWK 和 HELIOS 支架的弹性回缩百分比分别为 1.16%、2.62%、3.66%和 4.19%,表明 SYNERGY 的弹性回缩优于 FIREHAWK 和 HELIOS( < 0.05),这表明 XIENCE Xpedition 支架具有更好的通过能力。

结论

对包括通过能力、顺应性、弹性回缩和纵向强度在内的 38mm 长度支架的机械性能评估可为长病变治疗的更准确临床应用提供参考指标。

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