Clanner-Engelshofen Benjamin M, Marsela Enklajd, Engelsberger Nicole, Guertler Anne, Schauber Jürgen, French Lars E, Reinholz Markus
Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.
Heliyon. 2020 Mar 11;6(3):e03547. doi: 10.1016/j.heliyon.2020.e03547. eCollection 2020 Mar.
Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized.
To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease.
Data of 1124 patients with a confirmed diagnosis of CA, presenting in our university hospital outpatient consultation between 2011 and 2015 were retrospectively evaluated and the efficacy of various types of treatments was addressed.
A large patient cohort of 1124 predominately young (mean age 36.5 years old), male (83.9 %), single (50.2 %), heterosexual (92.8 %) Germans (62.5 %) received consults in our outpatient clinic for STDs. Nearly 60 % of the diagnosed patients presented with first-time CA, indicating a considerable proportion of roughly 40 % recurrent infections as well. Only 13.7 % of patients were previously immunized against HPV.
The evaluation of a large patient cohort provided a better understanding of the present epidemiology of CA in an outpatient hospital setting in Germany. An effective three-scale therapeutic regime and preventive measures were outlined.
肛门生殖器人乳头瘤病毒(HPV)感染是全球最常见的性传播疾病(STD)。在德国,HPV感染并无官方登记的义务,因此尖锐湿 疣(CA)的流行病学特征尚不明确。
更深入了解CA的流行病学情况,并概述针对该病患者可用的治疗方案。
回顾性评估了2011年至2015年间在我们大学医院门诊咨询中确诊为CA的1124例患者的数据,并探讨了各种治疗方法的疗效。
1124例患者组成的大型队列主要为年轻(平均年龄36.5岁)、男性(83.9%)、单身(50.2%)、异性恋(92.8%)的德国人(62.5%),他们在我们的门诊接受性传播疾病咨询。近60%的确诊患者为初次感染CA,这也表明约40%的复发感染比例相当可观。只有13.7%的患者之前接种过HPV疫苗。
对大型患者队列的评估有助于更好地了解德国一家门诊医院目前CA的流行病学情况。文中概述了一种有效的三级治疗方案和预防措施。