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2
Outcomes of interval appendectomy in comparison with appendectomy for acute appendicitis.间隔期阑尾切除术与急性阑尾炎阑尾切除术的疗效比较。
J Surg Res. 2018 May;225:90-94. doi: 10.1016/j.jss.2018.01.012. Epub 2018 Feb 21.
3
Occult Appendiceal Neoplasms in Acute and Chronic Appendicitis: A Single-Institution Experience of 1793 Appendectomies.急慢性阑尾炎中的隐匿性阑尾肿瘤:一家机构1793例阑尾切除术的经验
Am Surg. 2017 Dec 1;83(12):1381-1385.
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Increased incidence of bowel cancer after non-surgical treatment of appendicitis.阑尾炎非手术治疗后结直肠癌发病率增加。
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Ann Surg Oncol. 2017 Nov;24(12):3667-3672. doi: 10.1245/s10434-017-6052-7. Epub 2017 Aug 22.
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Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials.抗生素与阑尾切除术治疗单纯性急性阑尾炎的安全性和有效性比较:随机对照试验的荟萃分析。
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8
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南海岸阑尾周围肿物管理(SCAM)调查

South Coast appendicular mass management (SCAM) survey.

作者信息

Sajid Muhammad S, Ray Kausik, Hebbar Madhusoodhana, Riaz Waleed, Baig Mirza K, Sains Parv, Singh Krishna K

机构信息

Department of Digestive diseases, Brighton & Sussex University Hospitals NHS Trust, The Royal Sussex County Hospital, Brighton, West Sussex, UK.

Department of General and Laparoscopic Colorectal Surgery, Brighton & Sussex University Hospitals NHS Trust, The Royal Sussex County Hospital, Brighton, West Sussex, UK.

出版信息

Transl Gastroenterol Hepatol. 2020 Jan 5;5:4. doi: 10.21037/tgh.2019.11.07. eCollection 2020.

DOI:10.21037/tgh.2019.11.07
PMID:32190772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7061178/
Abstract

BACKGROUND

Management of appendicular mass and interval appendicectomy remains a controversial issue. Recent publication of a randomized controlled trial (RCT) reported the incidence of around 20% neoplastic lesions in the age group of more than forty years among the interval appendicectomy group against magnetic resonance imaging (MRI) surveillance only which led to trial termination. The objective of this study is to evaluate the current practice of the management of appendicular mass in five major hospitals of South Coast of the England.

METHODS

A proforma was designed and emailed to the general surgical department of five hospitals in the South Coast of England. The proforma completion rate and compliance were improved by direct telephone call to the on-call registrars and consultants to collect data.

RESULTS

Fifty-three surgeons (22 consultants, 27 ST3-ST8 grade surgical trainees and 4 SAS grades) completed the proforma. The clinical, hematological and computerized tomography (CT) based diagnostic criteria, and in-patient intravenous antibiotics (IV ABTXs) in addition to the radiological drainage in amenable cases for appendicular mass/abscess were mostly agreed initial management plan among surgeons. Normalization of inflammatory markers and radiological resolution were agreed discharge indicators. Agreed follow up investigations were CT scan (by 23%), Colonoscopy (by 13%), and both CT and colonoscopy (by 57%) after discharging patients. Only 17% surgeons offered planned interval appendicectomy and 62% surgeons offered interval appendectomy in selective cases of appendicular mass within 6 weeks to 6 months after discharge.

CONCLUSIONS

South Coast appendicular mass management (SCAM) survey confirms diverse practice to manage appendicular mass/abscess among surgeons working in South Coast hospitals. A substantial percentage of surgeons do not offer interval appendectomy to patients potentially leaving neoplastic lesions .

摘要

背景

阑尾包块的处理及间隔期阑尾切除术仍然是一个有争议的问题。最近一项随机对照试验(RCT)的发表报告称,间隔期阑尾切除术组中年龄超过40岁的人群中,与仅接受磁共振成像(MRI)监测相比,肿瘤性病变的发生率约为20%,这导致试验终止。本研究的目的是评估英格兰南海岸五家主要医院对阑尾包块的当前处理方法。

方法

设计了一份表格并通过电子邮件发送给英格兰南海岸五家医院的普通外科。通过直接给值班住院医师和顾问打电话收集数据,提高了表格的填写率和依从性。

结果

53名外科医生(22名顾问医生、27名ST3 - ST8级外科住院医师和4名SAS级医生)完成了表格。基于临床、血液学和计算机断层扫描(CT)的诊断标准,以及在适合的阑尾包块/脓肿病例中,除了进行放射引流外,住院期间使用静脉抗生素(IV ABTXs),大多是外科医生一致认可的初始处理方案。炎症标志物正常化和影像学消退是一致认可的出院指标。患者出院后,一致认可的后续检查是CT扫描(23%)、结肠镜检查(13%)以及CT和结肠镜检查(57%)。只有17%的外科医生提供计划性间隔期阑尾切除术,62%的外科医生在出院后6周至6个月的选择性阑尾包块病例中提供间隔期阑尾切除术。

结论

南海岸阑尾包块处理(SCAM)调查证实,在南海岸医院工作的外科医生中,处理阑尾包块/脓肿的方法存在差异。相当一部分外科医生没有为患者提供间隔期阑尾切除术,这可能会留下肿瘤性病变。