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经肛门引流管:直肠癌手术中作为去功能化造口的替代选择?

Transanal drainage tube: alternative option to defunctioning stoma in rectal cancer surgery?

作者信息

Carboni Fabio, Valle Mario, Levi Sandri Giovanni Battista, Giofrè Manuel, Federici Orietta, Zazza Settimio, Garofalo Alfredo

机构信息

Department of Digestive Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

出版信息

Transl Gastroenterol Hepatol. 2020 Jan 5;5:6. doi: 10.21037/tgh.2019.10.16. eCollection 2020.

Abstract

BACKGROUND

Anastomotic leakage (AL) remains the most dreaded complication after rectal cancer surgery. The aim of this study was to evaluate the role of transanal drainage tube in reducing the incidence, severity and hospital costs respect to defunctioning stoma (DS).

METHODS

Considering 429 patients consecutively operated for rectal adenocarcinoma, the tube was placed in 275 (Group A) and not placed in 154 (Group B) patients. A DS was created in a subgroup of 54 patients among the latter.

RESULTS

The incidence of AL was significantly higher in Group B (P=0.007). In patients with DS, the incidence was higher than Group A (P=NS). Grade C complications were significantly higher in Group B (P=0.006) and Grade B complications were significantly higher in patients with DS (P=0.03). Estimated economic benefit was 4,000 Euros for each patient.

CONCLUSIONS

Transanal drainage tube may be a safe and effective alternative to DS in many cases. The incidence of leakage and Grade C complications are reduced albeit not significantly but Grade B complications are significantly lower. Although the AL incidence was similar in our experience, the tube allows to avoid a stoma-related consequence and the need for reversal procedure with economic benefit.

摘要

背景

吻合口漏(AL)仍然是直肠癌手术后最可怕的并发症。本研究的目的是评估经肛门引流管在降低吻合口漏发生率、严重程度及住院费用方面相对于造口减压(DS)的作用。

方法

连续纳入429例行直肠腺癌手术的患者,其中275例患者放置了引流管(A组),154例患者未放置引流管(B组)。后一组中有54例患者行造口减压术。

结果

B组吻合口漏的发生率显著更高(P = 0.007)。行造口减压术的患者中,吻合口漏的发生率高于A组(P =无统计学意义)。B组C级并发症显著更多(P = 0.006),而行造口减压术的患者B级并发症显著更多(P = 0.03)。估计每位患者的经济效益为4000欧元。

结论

在许多情况下,经肛门引流管可能是造口减压术的一种安全有效的替代方法。虽然漏出率和C级并发症的发生率有所降低,但差异不显著,而B级并发症显著更低。尽管根据我们的经验吻合口漏发生率相似,但引流管可避免与造口相关的后果以及回纳手术的需要,并具有经济效益。

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