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噬菌体鸡尾酒疗法:多种抑制致病性的方法。

Phage Cocktail Therapy: Multiple Ways to Suppress Pathogenicity.

机构信息

National Key Laboratory of Wheat and Maize Crop Science, College of Life Sciences, Henan Agricultural University, Zhengzhou 450002, People's Republic of China.

Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.

出版信息

Trends Plant Sci. 2020 Apr;25(4):315-317. doi: 10.1016/j.tplants.2020.01.013. Epub 2020 Feb 12.

DOI:10.1016/j.tplants.2020.01.013
PMID:32191865
Abstract

Phage cocktails have emerged as precision tools for controlling plant bacterial diseases. Wang et al. now report that phage cocktails decreased the occurrence of tomato bacterial wilt disease efficiently by infecting and destroying bacterial pathogens, selecting phage-resistant but slow-growing pathogen strains, and fostering bacterial species that are antagonistic to the pathogens.

摘要

噬菌体鸡尾酒已成为控制植物细菌性疾病的精准工具。现在,Wang 等人报告称,噬菌体鸡尾酒通过感染和破坏病原菌、筛选对噬菌体有抗性但生长缓慢的病原菌菌株以及促进对病原菌具有拮抗作用的细菌物种,有效地降低了番茄细菌性萎蔫病的发生。

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