Henry Ford Health System, Detroit, MI, USA.
Wayne State University, Detroit, MI, USA.
Int J Surg Pathol. 2020 Sep;28(6):678-682. doi: 10.1177/1066896920912485. Epub 2020 Mar 19.
Cranial fasciitis is an uncommon benign fibroblastic tumor, generally histologically identical to nodular fasciitis. It develops almost exclusively in children. Cranial fasciitis manifests clinically as a painless rapidly growing solitary nodule in the head and neck area, frequently eroding the underlying bone. Thus, this entity is often confused with aggressive lesions such as sarcomas, both clinically and radiologically. Histopathologic examination is essential to differentiate between cranial fasciitis and fibrohistiocytic or even sarcomatous lesions observed in children. In this article, we present a case of cranial fasciitis with intracranial extension in a 2-year-old boy. Although rearrangement has recently been recognized as a recurring alteration in nodular fasciitis, we present a novel fusion in this lesion.
头部筋膜炎是一种不常见的良性纤维母细胞肿瘤，在组织学上通常与结节性筋膜炎相同。它几乎只发生在儿童中。头部筋膜炎临床上表现为头部和颈部无痛性快速生长的孤立性结节，常侵蚀下方的骨骼。因此，该疾病在临床上和影像学上常与肉瘤等侵袭性病变相混淆。组织病理学检查对于区分头部筋膜炎与纤维组织细胞性病变甚至肉瘤性病变是必要的。本文报道了一例 2 岁男孩头部筋膜炎伴颅内侵犯。虽然最近已经认识到基因重排是结节性筋膜炎的一种常见改变，但我们在此病变中发现了一种新的融合。
