King Khalid University, Abha, Saudi Arabia.
King Khalid University, Abha, Saudi Arabia.
J Infect Public Health. 2020 Aug;13(8):1172-1175. doi: 10.1016/j.jiph.2020.01.312. Epub 2020 Mar 17.
Hospital-acquired infections in the Intensive Care Unit (ICU) account for an increase in morbidity and mortality leading to serious health complications. This study aims to determine the effect of a multimodality approach including disinfection and physical separation on the infections prevailing in ICU.
The study employed prospective cross-over analysis to assess the 738 individuals (560 males and 178 females) at the ICU, Aseer Central Hospital, Saudi Arabia. The intervention programs were carried out for 3 years (2013-2015). It included the application of hydrogen peroxide and silver cations, physical separation, and compartmentalization of ICU. Acinetobacter spp., E. coli, and staphylococci were isolated, identified, and used to evaluate the efficacy of the intervention program.
The results provide endotracheal tube as the main specimen type (34.7%) followed by blood (29.1%), tracheal secretion (7.7%), wound (6%), urine (5.7%), throat swab (5.4%), sputum (3.7%), and other specimens (7.7%). It also showed the infection rate decreased from 14.3% to 4% in the last three months after continuous interventions (R = 0.44). There was a decrease in the occurrence of bacteria after an intervention (p = 0.036).
The outcome of the study revealed that mist and separation measures offered a significant decrease in infections at the ICU as per the measurement of the most hazardous nosocomial pathogens.
重症监护病房（ICU）获得性感染会导致发病率和死亡率增加，并导致严重的健康并发症。本研究旨在确定包括消毒和物理隔离在内的多模式方法对 ICU 流行感染的影响。
该研究采用前瞻性交叉分析评估了沙特阿拉伯阿西尔中央医院 ICU 的 738 名个体（560 名男性和 178 名女性）。干预计划持续了 3 年（2013-2015 年）。它包括应用过氧化氢和银离子、物理隔离和 ICU 的分区。分离、鉴定不动杆菌属、大肠杆菌和葡萄球菌，并用于评估干预计划的效果。
结果显示，主要标本类型为气管内导管（34.7%），其次为血液（29.1%）、气管分泌物（7.7%）、伤口（6%）、尿液（5.7%）、咽喉拭子（5.4%）、痰（3.7%）和其他标本（7.7%）。结果还显示，连续干预后的最后三个月感染率从 14.3%降至 4%（R=0.44）。干预后细菌的发生减少（p=0.036）。
研究结果表明，根据最危险的医院获得性病原体的测量，喷雾和分离措施显著降低了 ICU 的感染。
