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评估多发性骨髓瘤患者通过门诊护理进行自体干细胞移植途径的安全性。

Assessing the safety of autologous stem cell transplant pathway via ambulatory care for patients with multiple myeloma.

机构信息

Department of Haematology, University College London Hospitals, London, United Kingdom.

Department of Haematology, University College London Hospitals, London, United Kingdom.

出版信息

Hematol Oncol Stem Cell Ther. 2021 Jun;14(2):160-162. doi: 10.1016/j.hemonc.2020.01.001. Epub 2020 Mar 12.

DOI:10.1016/j.hemonc.2020.01.001
PMID:32192978
Abstract

High-dose chemotherapy (HDT) with autologous stem cell transplantation (ASCT) is the standard of care for eligible multiple myeloma (MM) patients with improved progression-free and overall survival. We reviewed the ambulatory care unit pathway for MM patients who underwent HDT/ASCT in a tertiary hospital to assess safety efficacy and outcomes. We concluded that the ambulatory care model offered for MM patients undergoing HDT/ASCT is a safe alternative pathway and highlighted further improvements.

摘要

大剂量化疗(HDT)联合自体干细胞移植(ASCT)是适合的多发性骨髓瘤(MM)患者的标准治疗方法,可以改善无进展生存期和总生存期。我们回顾了在一家三级医院接受 HDT/ASCT 的 MM 患者的门诊护理路径,以评估其安全性、疗效和结果。我们的结论是,为接受 HDT/ASCT 的 MM 患者提供的门诊护理模式是一种安全的替代途径,并强调了进一步的改进。

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Assessing the safety of autologous stem cell transplant pathway via ambulatory care for patients with multiple myeloma.评估多发性骨髓瘤患者通过门诊护理进行自体干细胞移植途径的安全性。
Hematol Oncol Stem Cell Ther. 2021 Jun;14(2):160-162. doi: 10.1016/j.hemonc.2020.01.001. Epub 2020 Mar 12.
2
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Benefits of Autologous Stem Cell Transplantation for Elderly Myeloma Patients in the Last Quarter of Life.自体干细胞移植对老年骨髓瘤患者生命最后一个季度的益处。
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ThaDD plus high dose therapy and autologous stem cell transplantation does not appear superior to ThaDD plus maintenance in elderly patients with de novo multiple myeloma.在初治老年多发性骨髓瘤患者中,ThaDD 联合大剂量化疗和自体造血干细胞移植似乎并不优于 ThaDD 联合维持治疗。
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Chemotherapy plus lenalidomide versus autologous transplantation, followed by lenalidomide plus prednisone versus lenalidomide maintenance, in patients with multiple myeloma: a randomised, multicentre, phase 3 trial.来那度胺联合化疗与自体移植,随后来那度胺联合泼尼松与来那度胺维持治疗多发性骨髓瘤患者:一项随机、多中心、3 期试验。
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Second autologous stem cell transplantation as salvage therapy for multiple myeloma: impact on progression-free and overall survival.自体干细胞移植作为多发性骨髓瘤挽救疗法的第 2 次治疗:对无进展生存期和总生存期的影响。
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引用本文的文献

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Autologous stem cell transplantation for multiple myeloma patients whose myeloma-defining event was SLiM.对于骨髓瘤定义事件为SLiM的多发性骨髓瘤患者进行自体干细胞移植。
Br J Haematol. 2025 Feb;206(2):607-614. doi: 10.1111/bjh.19936. Epub 2024 Nov 29.
2
Ambulatory models for autologous stem-cell transplantation: a systematic review of the health impact.门诊自体干细胞移植模型:对健康影响的系统评价。
Front Immunol. 2024 Jul 16;15:1419186. doi: 10.3389/fimmu.2024.1419186. eCollection 2024.
3
Multiple Myeloma Outpatient Transplant Program in the Era of Novel Agents: State-of-the-Art.
新型药物时代的多发性骨髓瘤门诊移植项目:最新进展
Front Oncol. 2020 Nov 11;10:592487. doi: 10.3389/fonc.2020.592487. eCollection 2020.