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Daratumumab inhibits acute myeloid leukaemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells.

作者信息

Mistry Jayna J, Moore Jamie A, Kumar Prakritt, Marlein Christopher R, Hellmich Charlotte, Pillinger Genevra, Jibril Aisha, Di Palma Federica, Collins Angela, Bowles Kristian M, Rushworth Stuart A

机构信息

University of East Anglia, Norwich Medical School.

Earlham Institute.

出版信息

Haematologica. 2021 Feb 1;106(2):589-592. doi: 10.3324/haematol.2019.242974.

DOI:10.3324/haematol.2019.242974
PMID:32193250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7849566/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/6a4baad40248/106589.fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/c59faf351b7a/106589.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/a70507820e79/106589.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/6a4baad40248/106589.fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/c59faf351b7a/106589.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/a70507820e79/106589.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/474b/7849566/6a4baad40248/106589.fig3.jpg

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Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24610-24619. doi: 10.1073/pnas.1913278116. Epub 2019 Nov 14.
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CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma.CD38 驱动的线粒体转运促进多发性骨髓瘤中的生物能量可塑性。
Cancer Res. 2019 May 1;79(9):2285-2297. doi: 10.1158/0008-5472.CAN-18-0773. Epub 2019 Jan 8.
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Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia.
Cancers (Basel). 2024 Oct 28;16(21):3627. doi: 10.3390/cancers16213627.
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Remodeling of the bone marrow microenvironment during acute myeloid leukemia progression.急性髓系白血病进展过程中骨髓微环境的重塑
Ann Transl Med. 2024 Aug 1;12(4):63. doi: 10.21037/atm-23-1824. Epub 2024 Jan 15.
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Front Oncol. 2023 Sep 7;13:1244280. doi: 10.3389/fonc.2023.1244280. eCollection 2023.
维奈托克联合地西他滨或阿扎胞苷治疗初治老年急性髓系白血病患者。
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The bone marrow microenvironment - Home of the leukemic blasts.骨髓微环境——白血病细胞的发源地。
Blood Rev. 2017 Sep;31(5):277-286. doi: 10.1016/j.blre.2017.03.004. Epub 2017 Mar 12.
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Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.一些核仁磷酸蛋白（nucleophosmin）突变的急性髓系白血病患者的白血病起始细胞位于 CD34(-) 细胞群中。
Blood. 2010 Mar 11;115(10):1976-84. doi: 10.1182/blood-2009-02-206565. Epub 2010 Jan 6.