Department of Neurosurgery, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.
Center for Medical Decision Making, Department of Public Health, Erasmus MC University Medical Center, Doctor Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.
Acta Neurochir (Wien). 2020 Sep;162(9):2235-2244. doi: 10.1007/s00701-020-04290-0. Epub 2020 Mar 19.
The membrane of Liliequist is one of the best-known inner arachnoid membranes and an essential intraoperative landmark when approaching the interpeduncular cistern but also an obstacle in the growth of lesions in the sellar and parasellar regions. The limits and exact anatomical description of this membrane are still unclear, as it blends into surrounding structures and joins other arachnoid membranes.
We performed a systematic narrative review by searching for articles describing the anatomy and the relationship of the membrane of Liliequist with surrounding structures in MEDLINE, Embase and Google Scholar. Included articles were cross-checked for missing references. Both preclinical and clinical studies were included, if they detailed the clinical relevance of the membrane of Liliequist.
Despite a common definition of the localisation of the membrane of Liliequist, important differences exist with respect to its anatomical borders. The membrane appears to be continuous with the pontomesencephalic and pontomedullary membranes, leading to an arachnoid membrane complex around the brainstem. Furthermore, Liliequist's membrane most likely continues along the oculomotor nerve sheath in the cavernous sinus, blending into and giving rise to the carotid-oculomotor membrane.
Further standardized anatomical studies are needed to clarify the relation of the membrane of Liliequist with surrounding structures but also the anatomy of the arachnoid membranes in general. Our study supports this endeavour by identifying the knowledge hiatuses and reviewing the current knowledge base.
Liliequist 膜是最著名的蛛网膜内膜之一，在接近脚间池时是重要的术中标志，但也是鞍区和鞍旁区域病变生长的障碍。该膜的界限和确切解剖描述尚不清楚，因为它与周围结构融合，并与其他蛛网膜膜结合。
我们通过在 MEDLINE、Embase 和 Google Scholar 中搜索描述 Liliequist 膜解剖结构及其与周围结构关系的文章，进行了系统的叙述性综述。对纳入的文章进行了交叉核对，以检查是否遗漏了参考文献。纳入了临床前和临床研究，如果它们详细说明了 Liliequist 膜的临床相关性。
尽管对 Liliequist 膜的定位有一个共同的定义，但在其解剖边界上存在重要差异。该膜似乎与脑桥的脑桥正中膜和脑桥延髓膜连续，导致围绕脑干的蛛网膜膜复合体。此外，Liliequist 膜很可能沿着海绵窦中的动眼神经鞘延伸，与颈动脉-动眼神经膜融合并形成该膜。
需要进一步的标准化解剖研究来阐明 Liliequist 膜与周围结构的关系，以及蛛网膜膜的一般解剖结构。我们的研究通过确定知识空白并回顾当前知识库，支持了这一努力。
