Institute of Cell Biophysics, Russian Acad. Sci., Institutskaya st. 3, Pushchino, Moscow Region 142290, Russia.
Tula State Lev Tolstoy Pedagogical University, Prospekt Lenina, 125, Tula 300026, Russia.
Microvasc Res. 2020 Jul;130:103993. doi: 10.1016/j.mvr.2020.103993. Epub 2020 Mar 17.
The influence of deep controlled respiration on cardiovascular oscillations in 13 healthy young volunteers was studied. A measurement system comprising electrocardiography, laser Doppler flowmetry (LDF) and photoplethysmography (PPG) was used to estimate heart rate variability (HRV), tissue blood volume and skin blood perfusion at spontaneous respiration and during three tests at controlled conditions. In the latter case, respiration was controlled in both rate (0.04, 0.1 and 0.25 Hz) and depth. During respiration at 0.04 and 0.1 Hz, the amplification of a respiratory-related component in the spectra of HRV and PPG signals turned out to be more significant than that at spontaneous respiration, and at 0.25 Hz this component remained unchanged. Controlled respiration caused a significant increase in correlation in HRV-PPG, HRV-LDF and PPG-LDF pairs of signals compared to spontaneous one. At 0.25 Hz controlled respiration, no significant increase in correlation in these pairs of signals was found. The differences observed in this study can be attributed to the effects of the sympathetic nerve activity on vascular tone regulation.
研究了 13 名健康年轻志愿者深度控制呼吸对心血管振荡的影响。使用包含心电图、激光多普勒流量测量（LDF）和光体积描记（PPG）的测量系统来估计心率变异性（HRV）、组织血液体积和皮肤血液灌注，分别在自主呼吸和受控条件下的三项测试中进行。在后一种情况下，呼吸的频率（0.04、0.1 和 0.25 Hz）和深度都受到控制。在 0.04 和 0.1 Hz 的呼吸过程中，HRV 和 PPG 信号频谱中与呼吸相关的分量的放大程度比自主呼吸时更为显著，而在 0.25 Hz 时该分量保持不变。与自主呼吸相比，受控呼吸使 HRV-PPG、HRV-LDF 和 PPG-LDF 信号对的相关性显著增加。在 0.25 Hz 的受控呼吸下，这些信号对的相关性没有显著增加。本研究中观察到的差异可归因于交感神经活动对血管张力调节的影响。
