Allen Loyd V
International Journal of Pharmaceutical Compounding.
Int J Pharm Compd. 2020 Mar-Apr;24(2):121-126.
The study of intravenous admixture compatibility is an excellent application of "clinical pharmaceutics." Clinical pharmaceutics involves the study and application of pharmaceutics and pharmaceutic (physical pharmacy/ chemistry) principles to clinical compounding situations to aid in the evaluation of each intravenous admixture. This series includes compatibility and stability considerations in intravenous admixture compounding. Part 2 of this series of articles discussed many factors that should be considered that may give rise to compatibility concerns, as well as drug sorption issues. In this issue (Part 3), there is a discussion on the methods and techniques that can be used to decrease the occurrence and incidence of incompatibilities, along with some alternate techniques to consider when some approaches do not seem feasible.
静脉药物混合配伍性研究是“临床药剂学”的一个出色应用。临床药剂学涉及将药剂学和药学（物理药学/化学）原理研究与应用于临床配药情况，以协助评估每种静脉药物混合液。本系列包括静脉药物混合液配制中的配伍性和稳定性考量。本系列文章的第2部分讨论了许多可能引发配伍性问题的应考虑因素，以及药物吸附问题。在本期（第3部分）中，将讨论可用于减少配伍禁忌发生和发生率的方法与技术，以及在某些方法似乎不可行时可考虑的一些替代技术。
