Allen Loyd V
International Journal of Pharmaceutical Compounding.
Int J Pharm Compd. 2023 Sep-Oct;27(5):397-409.
Intravenous admixture compounding is common practice in most hospitals throughout the world, regardless of the country. Compounding intravenous medications involves risk, as there is a high potential for error due to their complexity in compounding as well as the additional issues that working in an aseptic compounding environment poses for the compounder. This article in a series of intravenous admixture compounding discusses considerations involved when using commercial products in compounding, as well as a discussion on the issues of freezing, solubility, sorption, leaching, incompatibilities, and quality control, with an emphasis on physicochemical considerations.
静脉药物混合配制在世界上大多数医院都是常见的做法，不分国家。配制静脉用药存在风险，因为其配制复杂，而且在无菌配制环境中工作给配制人员带来额外问题，所以出错可能性很大。本系列关于静脉药物混合配制的文章讨论了在配制中使用商业产品时涉及的注意事项，以及关于冷冻、溶解度、吸附、浸出、配伍禁忌和质量控制等问题，重点是物理化学方面的考虑因素。
