Rogers-Smith E, Hammerton R, Mathis A, Allison A, Clark L
Internal Medicine, Davies Veterinary Specialists, Higham Gobion, SG53HR, UK.
Anaesthesia, Willows Veterinary Centre and Referral Service, Solihull, B90 4NH, UK.
J Small Anim Pract. 2020 Jun;61(6):363-367. doi: 10.1111/jsap.13134. Epub 2020 Mar 20.
To characterise common factors after a suspected increase in the incidence of post-procedure acute kidney injury in healthy dogs presenting for non-emergency surgical procedures.
Retrospective analysis of the medical records of 12 dogs that presented for acute kidney injury after general anaesthesia for non-emergency surgical procedures.
The 12 non-geriatric dogs re-presented with acute kidney injury at a median of 4 days after surgery to four different veterinary centres, including three multidisciplinary referral practices in the UK. All dogs in this case series weighed more than 20 kg and had a median age of 17 months. There was no apparent association with breed, type of surgery, duration of anaesthesia, perioperative drug choice or non-steroidal anti-inflammatory drug administration.
Although well-defined in human medicine, there is very little information regarding the association between general anaesthesia and acute kidney injury in animals. No definitive causal link was found in this case series. Clinicians with similar cases are requested to contact the corresponding author so a more representative incidence rate can be obtained.
对接受非紧急外科手术的健康犬术后急性肾损伤发病率疑似增加后的常见因素进行特征描述。
对12只接受非紧急外科手术全身麻醉后出现急性肾损伤的犬的病历进行回顾性分析。
这12只非老年犬在术后中位时间4天出现急性肾损伤，分别前往四个不同的兽医中心，包括英国的三家多学科转诊机构。该病例系列中的所有犬体重均超过20千克，中位年龄为17个月。与品种、手术类型、麻醉持续时间、围手术期药物选择或非甾体抗炎药的使用无明显关联。
虽然在人类医学中对此有明确界定，但关于动物全身麻醉与急性肾损伤之间的关联信息非常少。本病例系列未发现明确的因果关系。请求有类似病例的临床医生联系通讯作者，以便获得更具代表性的发病率。
