Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, 325027, China.
Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, 325027, China.
Int J Surg. 2020 May;77:40-47. doi: 10.1016/j.ijsu.2020.03.016. Epub 2020 Mar 17.
To determine whether preoperative warming can reduce the risk of surgical site infection (SSI) after surgery.
Intraoperative hypothermia is a risk factor for the occurrence of SSI in patients after surgery. However, the effectiveness of preoperative warming in reducing the incidence of the condition remains unclear.
A systematic review was conducted using Medline, EMBASE, and the Cochrane Library to identify randomized controlled trials (RCTs) that evaluated the risk of SSI after surgery with and without the use of a preoperative warming protocol. The primary outcome measure was the diagnosis of SSI within 10-90 days of surgery. The pooled risk ratio was estimated with a fixed-effect meta-analysis. Sensitivity analyses were performed to examine the impact of the structural design of preoperative warming on the pooled risk of SSI.
Of the 249 studies identified, seven RCTs representing 1086 patients were included in the present meta-analysis. The use of preoperative warming was associated with a significant decrease in SSI (RR = 0.60, 95% CI 0.42-0.87, P = 0.072). Specifically, we defined patients who used forced-air warming (FAW) and integrated measures such as liquid heating and warming blankets as the MIX group and patients who used only FAW as the FAW group. Patients who used MIX methods (temperature set <43 °C and 30-min prewarming) before surgery benefited more from prewarming.
The results of this study suggest that preoperative warming can reduce rates of SSI after surgery. We, therefore, recommend the application of MIX warming methods before surgery.
确定术前预热是否可以降低手术后手术部位感染(SSI)的风险。
术中低体温是术后患者发生 SSI 的危险因素。然而,术前预热降低该疾病发病率的有效性尚不清楚。
使用 Medline、EMBASE 和 Cochrane 图书馆系统地回顾了评估使用和不使用术前预热方案后手术中 SSI 风险的随机对照试验(RCT)。主要观察指标为手术后 10-90 天内 SSI 的诊断。使用固定效应荟萃分析估计合并风险比。进行敏感性分析以检查术前预热结构设计对合并 SSI 风险的影响。
在确定的 249 项研究中,有 7 项 RCT 代表 1086 名患者纳入了本次荟萃分析。使用术前预热与 SSI 显著降低相关(RR=0.60,95%CI 0.42-0.87,P=0.072)。具体而言,我们将使用强制空气加热(FAW)和液体加热和加热毯等综合措施的患者定义为 MIX 组,仅使用 FAW 的患者定义为 FAW 组。在手术前使用 MIX 方法(设定温度<43°C 和 30 分钟预热)的患者从预热中获益更多。
本研究结果表明,术前预热可降低手术后 SSI 的发生率。因此,我们建议在手术前应用 MIX 预热方法。