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术中低体温与手术部位感染发生之间的关系:一项观察性研究的荟萃分析

The relationship between intraoperative hypothermia and the ccurrence of surgical site infections: a meta-analysis of observational studies.

作者信息

Ju Jing, Zhou Feng, Wang Zhenzhi

机构信息

Operation Room, Rainbow Hospital of Xianyang, Xianyang, Shaanxi Province, China.

The Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi Province, China.

出版信息

Front Surg. 2024 Jul 11;11:1436366. doi: 10.3389/fsurg.2024.1436366. eCollection 2024.

Abstract

OBJECTIVE

Inconsistent evidence exists regarding the association between intraoperative hypothermia and incidence of surgical site infection (SSI). This study aimed to determine the association between intraoperative hypothermia and SSI.

MATERIALS AND METHODS

A systematic review was conducted using Embase, PubMed, and Web of Science to identify observational studies evaluating the risk of SSI in patients with intraoperative hypothermia. The primary outcome measure was the diagnosis of SSI within 30 days of surgery. The pooled risk ratio was estimated using a fixed- or random-effect meta-analysis. Sensitivity analyses were performed to examine the impact of the structural design of preoperative warming on the pooled risk of SSI.

RESULTS

Five studies representing 6,002 patients were included in the present meta-analysis. Intraoperative hypothermia was not associated with SSI risk in patients (HR = 1.22, 95% CI: 0.95-2.24, = 0.119). The pooled hazard ratio showed that intraoperative hypothermia did not result in a higher risk of SSI.

CONCLUSIONS

Intraoperative hypothermia was not associated with the risk of SSI. Further studies using objective exposure measurements are required to confirm these results.

摘要

目的

关于术中低体温与手术部位感染(SSI)发生率之间的关联,证据并不一致。本研究旨在确定术中低体温与SSI之间的关联。

材料与方法

使用Embase、PubMed和Web of Science进行系统综述,以识别评估术中低体温患者发生SSI风险的观察性研究。主要结局指标是术后30天内SSI的诊断。采用固定效应或随机效应荟萃分析估计合并风险比。进行敏感性分析以检验术前保暖的结构设计对SSI合并风险的影响。

结果

本荟萃分析纳入了五项研究,共6002例患者。术中低体温与患者的SSI风险无关(HR = 1.22,95% CI:0.95 - 2.24,P = 0.119)。合并风险比显示术中低体温不会导致更高的SSI风险。

结论

术中低体温与SSI风险无关。需要进一步使用客观暴露测量的研究来证实这些结果。

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