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一例18年间确诊的上颌骨巨大骨化性纤维瘤合并孤立性骨囊肿:病例报告

A large maxillary cemento-ossifying fibroma superimposed with solitary bone cyst documented over 18 years: A case report.

作者信息

Aburas Sarmad, Bandura Patrick, Al-Ibraheem Ali, Berger Sebastian, Meier Marius, Turhani Dritan

机构信息

Centre for Oral and Maxillofacial Surgery, University of Dental Medicine and Oral Health, Danube Private University, Steiner Landstraße 124, 3500 Krems-Stein, Austria.

Centre for Oral and Maxillofacial Surgery, University of Dental Medicine and Oral Health, Danube Private University, Steiner Landstraße 124, 3500 Krems-Stein, Austria.

出版信息

Int J Surg Case Rep. 2020;68:257-262. doi: 10.1016/j.ijscr.2020.03.011. Epub 2020 Mar 7.

Abstract

INTRODUCTION

Cemento-ossifying fibromas are rare, benign lesions of the head and neck regions. The origin of these lesions can be traced to the periodontal ligament, because its cells are able to form cement, lamellar bone, or fibrous tissue.

CASE PRESENTATION

A rare case report of a young Caucasian female with a COF is described including follow-ups. She remained untreated for several years despite early radiographic findings of the lesion without a definitive diagnosis. The patient ultimately underwent radical surgery and the whole lesion was removed. The subsequent histological examination confirmed the clinical diagnosis of a COF. Since then, the patient has been under regular clinical and radiological follow-ups.

DISCUSSION

This rare case report of a COF, documented over 18 years, shows the importance of consecutive therapy after radiologic and clinical findings, as such lesions continue growing and may subsequently lead to severe medical conditions. Therefore, complete surgical resection of COFs is advised to achieve good results in terms of health and recurrence.

CONCLUSION

Long-term follow-up of patients is required as recurrences can occur for up to 10 years following treatment. Well-planned radical and wide surgical resection of these lesions has proven not only to be effective in eliminating the aetiological factors, but can also achieve decent bone regeneration and aesthetic results with almost no deformation in the surgical site.

摘要

引言

骨化性纤维瘤是头颈部罕见的良性病变。这些病变的起源可追溯至牙周韧带,因为其细胞能够形成牙骨质、板层骨或纤维组织。

病例报告

描述了一例年轻白种女性患骨化性纤维瘤的罕见病例报告,包括随访情况。尽管早期影像学检查发现了病变但未明确诊断,该患者多年来一直未接受治疗。患者最终接受了根治性手术,整个病变被切除。随后的组织学检查证实了骨化性纤维瘤的临床诊断。从那时起,患者一直接受定期的临床和放射学随访。

讨论

这份记录了18年的骨化性纤维瘤罕见病例报告显示,根据影像学和临床检查结果进行连续治疗非常重要,因为此类病变会持续生长,随后可能导致严重的健康问题。因此,建议对骨化性纤维瘤进行完整的手术切除,以在健康和复发方面取得良好效果。

结论

由于治疗后长达10年都可能出现复发,因此需要对患者进行长期随访。事实证明,精心规划的根治性广泛手术切除不仅能有效消除病因,还能实现良好的骨再生和美学效果,手术部位几乎没有变形。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfb8/7082601/41164cb19567/gr1.jpg

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