Sobrino Prados Almudena, Eizaguirre Zarza Beatriz, Gimeno Esteras Esther, Del Agua Arias-Camisón Celia
Departamento de Anatomía Patológica, Hospital Universitario Miguel Servet, Zaragoza, Aragón, España.
Departamento de Anatomía Patológica, Hospital Universitario Miguel Servet, Zaragoza, Aragón, España.
Rev Esp Patol. 2020 Apr-Jun;53(2):117-120. doi: 10.1016/j.patol.2019.02.002. Epub 2019 Apr 10.
Secretory carcinoma of the breast is a rare entity, characterized by the presence of intra- and extracellular, eosinophilic and acelular secretions. They are negative for hormone receptors and do not express human epidermal growth factor receptor HER-2/neu. However, the clinical outcome is favorable. Multicentricity is very unusual. We report a case of a 32-year-old woman with a multicentric secretory carcinoma of the breast. The main pathological features are discussed together with a review of the pertinent literature.
乳腺分泌性癌是一种罕见的疾病,其特征是存在细胞内和细胞外的嗜酸性无细胞分泌物。它们对激素受体呈阴性,不表达人表皮生长因子受体HER-2/neu。然而,临床结果良好。多中心性非常罕见。我们报告一例32岁女性的多中心性乳腺分泌性癌病例。主要病理特征与相关文献综述一并讨论。