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湿热交换器对异氟烷麻醉犬吸入气体温度和湿度的影响。

Effect of a heat and moisture exchanger on temperature and humidity of inhaled gas in isoflurane-anesthetized dogs.

机构信息

Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan; Department of Comparative Animal Science, College of Life Science, Kurashiki University of Science and the Arts, Kurashiki, Okayama, Japan.

Department of Comparative Animal Science, College of Life Science, Kurashiki University of Science and the Arts, Kurashiki, Okayama, Japan.

出版信息

Vet Anaesth Analg. 2020 May;47(3):377-380. doi: 10.1016/j.vaa.2020.02.003. Epub 2020 Feb 26.

Abstract

OBJECTIVE

To investigate the effects of a heat and moisture exchanger (HME) on the temperature and humidity of inhaled gas in isoflurane-anesthetized dogs.

STUDY DESIGN

Prospective, interventional study.

ANIMALS

A total of four experimental dogs and four client-owned dogs weighing 13.9 ± 7.4 kg (mean ± standard deviation).

METHODS

The four experimental dogs were anesthetized on two occasions with and without an intact HME at least 1 week apart. The four client-owned dogs were anesthetized once only for a surgical procedure and assigned to the HME group or no-HME group in alternate order, resulting in six dogs for each group. All dogs were premedicated, anesthetized with propofol and intubated. The HME was connected to the endotracheal tube. Anesthesia was maintained with isoflurane. A digital thermo-hygrometer was placed between the endotracheal tube and HME. The temperature and relative humidity of the inhaled gas were measured every 5 minutes for 60 minutes and the absolute humidity was calculated at each time point.

RESULTS

The temperature and absolute humidity of the inhaled gas was significantly higher at 5-60 minutes after intubation in the HME group than in the no-HME group. Absolute humidity was maintained above 29 mg HO L in the HME group. No significant time-dependent effects on temperature, relative humidity or absolute humidity of the inhaled gas were observed.

CONCLUSIONS AND CLINICAL RELEVANCE

The temperature and absolute humidity of the inhaled gas were higher when an HME was used during isoflurane anesthesia in dogs. The use of an HME may reduce the risk of dehydration and dysfunction of the airway mucosal epithelium.

摘要

目的

研究热湿交换器(HME)对异氟醚麻醉犬吸入气体温度和湿度的影响。

研究设计

前瞻性、干预性研究。

动物

共 4 只实验犬和 4 只体重 13.9±7.4kg(平均值±标准差)的患犬。

方法

这 4 只实验犬在至少相隔 1 周的两次麻醉中分别使用和不使用完整的 HME。这 4 只患犬仅在一次手术麻醉中使用,按照 HME 组和无 HME 组交替的顺序分配,每组各有 6 只犬。所有犬均进行预给药,用丙泊酚麻醉并插管。将 HME 连接到气管导管上。在气管导管和 HME 之间放置数字温湿度计。测量吸入气体的温度和相对湿度,每 5 分钟测量 60 分钟,并在每个时间点计算绝对湿度。

结果

与无 HME 组相比,在 HME 组中,气管插管后 5-60 分钟时吸入气体的温度和绝对湿度显著更高。在 HME 组中,绝对湿度始终保持在 29mgHOL 以上。未观察到温度、相对湿度或吸入气体绝对湿度随时间的显著变化。

结论和临床相关性

在犬异氟醚麻醉期间使用 HME 时,吸入气体的温度和绝对湿度更高。使用 HME 可能会降低气道黏膜上皮脱水和功能障碍的风险。

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