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使用计算流体动力学可视化时间性血容量分布对梭形基底动脉干动脉瘤的血管内治疗决策。

Decision-making for endovascular treatment of a fusiform basilar trunk artery aneurysm with visualization of chronological blood mass distribution using computational fluid dynamics.

机构信息

Department of Neurosurgery, Mie Chuo Medical Center, 2158-5 Myojin-cho, Hisai, Tsu, Mie 514-1101, Japan.

Department of Neurosurgery, Mie Chuo Medical Center, 2158-5 Myojin-cho, Hisai, Tsu, Mie 514-1101, Japan.

出版信息

Clin Neurol Neurosurg. 2020 Jun;193:105780. doi: 10.1016/j.clineuro.2020.105780. Epub 2020 Mar 19.

DOI:10.1016/j.clineuro.2020.105780
PMID:32200218
Abstract

Fusiform basilar trunk artery aneurysms are rare lesions, to which stent-assisted coil embolization or flow diversion have been generally applied. When a stent is placed from the distal basilar artery or the posterior cerebral artery to the vertebral artery (VA) through a fusiform basilar artery aneurysm, the side of the VA may be determined according to its size, shape, accessibility and aneurysm projection. In the present report, we constructed stent-placement models from the distal basilar artery to either VA across the aneurysm, and investigated blood mass distribution using computational fluid dynamics. The results revealed more stagnated blood flow in the aneurysm after stenting to the left VA. According to the simulation, stent-assisted coil embolization of the aneurysm was performed, resulting in sufficient obliteration. This visualization technique could be useful for decision-making for the treatment of complicated aneurysms and has a wide range of potential applications.

摘要

梭形基底动脉干动脉瘤是一种罕见的病变,通常采用支架辅助线圈栓塞或血流转向治疗。当支架从远端基底动脉或大脑后动脉通过梭形基底动脉动脉瘤放置到椎动脉(VA)时,可根据 VA 的大小、形状、可及性和动脉瘤突出程度来确定 VA 的侧别。在本报告中,我们构建了从远端基底动脉到穿过动脉瘤的任一侧 VA 的支架放置模型,并使用计算流体动力学研究了血液质量分布。结果表明,支架置入到左侧 VA 后,动脉瘤内的血流更加停滞。根据模拟结果,对动脉瘤进行支架辅助线圈栓塞治疗,结果显示完全闭塞。这种可视化技术可能有助于治疗复杂动脉瘤的决策,并具有广泛的潜在应用。

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