General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
General Surgery Department, Faculty of Medicine, Helwan University, Helwan, Egypt.
Obes Surg. 2020 Jul;30(7):2676-2683. doi: 10.1007/s11695-020-04547-8.
Obesity has become a pandemic nowadays. Bariatric surgery is increasingly performed to manage obesity. Currently, laparoscopic sleeve gastrectomy (LSG) is a widely accepted procedure given its feasibility and efficacy. Previous studies revealed conflicting results regarding the change of gastric emptying following sleeve gastrectomy. The primary aim of the present study is to assess gastric motor function by gastric emptying scintigraphy in a cohort of non-diabetic patients undergoing laparoscopic sleeve gastrectomy (LSG) for treatment of severe obesity.
This prospective observational study included 100 obese, non-diabetic patients attending the surgery clinic at Cairo University Hospitals and Al Azhar University Hospitals. LSG was performed following a standardized protocol, with no complications observed. All patients had gastric emptying scintigraphy done through a standard semisolid meal (250 kcal), marked with 0.5 mCiTc 99, pre-operatively and 3 months after LSG.
The mean age was 38.71 years (9.2) and males comprised 57% of the cohort. The body mass index, low-density lipoproteins, and glycated hemoglobin declined significantly at 3-month postsurgery. The scintigraphy study revealed a significantly reduced percent retention at equivalent time points 3 months after LSG. In addition, the percent of patients suffering from GERD decreased significantly after LSG.
Gastric emptying becomes faster after LSG in morbidly obese non-diabetic patients. GERD symptoms improve after surgery.
肥胖如今已成为一种全球性的流行病。减重手术越来越多地被用于治疗肥胖症。目前，腹腔镜袖状胃切除术（LSG）因其可行性和疗效而被广泛接受。既往研究显示，袖状胃切除术后胃排空的变化结果存在差异。本研究的主要目的是通过胃排空闪烁显像术评估非糖尿病肥胖患者行腹腔镜袖状胃切除术（LSG）治疗重度肥胖后的胃动力功能。
本前瞻性观察性研究纳入了在开罗大学医院和爱资哈尔大学医院外科诊所就诊的 100 名肥胖非糖尿病患者。LSG 按照标准化方案进行，未观察到任何并发症。所有患者均在术前和 LSG 术后 3 个月行胃排空闪烁显像术，使用标准半固体餐（250 千卡）标记 0.5 mCiTc 99。
患者的平均年龄为 38.71 岁（9.2），男性占队列的 57%。术后 3 个月，体重指数、低密度脂蛋白和糖化血红蛋白显著下降。闪烁显像研究显示，LSG 术后在等效时间点的胃排空潴留百分比显著降低。此外，LSG 后胃食管反流病（GERD）患者的比例显著下降。
肥胖的非糖尿病患者行 LSG 后胃排空速度加快。术后 GERD 症状改善。
