Gray Katherine D, Moore Maureen D, Bellorin Omar, Abelson Jonathan S, Dakin Gregory, Zarnegar Rasa, Pomp Alfons, Afaneh Cheguevara
Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medicine, 1300 York Ave. A1027, New York, NY, 10065, USA.
, 525 E 68th St, Box 294, New York, NY, 10021, USA.
Obes Surg. 2018 Mar;28(3):636-642. doi: 10.1007/s11695-017-2904-2.
We sought to assess outcomes of laparoscopic sleeve gastrectomy (LSG) vs laparoscopic Roux-en-Y gastric bypass (LRYGB) in a cohort of morbidly obese, elderly patients.
Retrospective review was conducted of all patients age 60 years or greater undergoing LSG or LRYGB at our institution between 2007 and 2014.
A total of 134 patients who underwent LSG (n = 65) or LRYGB (n = 69) were identified. Groups were similar with respect to age (64 years, range 60-75 years), BMI (44.0 ± 6.1), and ASA score (91% ≥ ASA 3). There were no differences in major post-operative complications (3, 4.7% LSG vs 4, 5.8% LRYGB, p = 0.75). Median follow-up was 39 months (IQR 14-64 months) with no patients lost to follow-up. Patients undergoing LRYGB had improvement in each of diabetes mellitus 2 (DM2), hypertension (HTN), hyperlipidemia (HL), and gastroesophageal reflux disease (GERD) as well as a significant decrease in insulin use (16/47, 34.0% pre-operatively vs 7/47, 15.2% post-operatively; p = 0.03). Patients undergoing LSG had improvement in DM2 and HTN but not in HL or GERD; there was no reduction in insulin dependence. Weight loss was not significantly different between groups; mean percent total weight loss at 36 months was 26.9 ± 9.0% in the LSG group and 23.9 ± 9.3% in the LRYGB group, p = 0.24.
Both LSG and RYGB can be safely performed on morbidly obese, elderly adults. At intermediate follow-up, there is an increased metabolic benefit for elderly patients undergoing LRYGB over LSG.
我们试图评估在一组病态肥胖的老年患者中,腹腔镜袖状胃切除术(LSG)与腹腔镜Roux-en-Y胃旁路术(LRYGB)的治疗效果。
对2007年至2014年间在我院接受LSG或LRYGB手术的所有60岁及以上患者进行回顾性研究。
共确定了134例行LSG(n = 65)或LRYGB(n = 69)的患者。两组在年龄(64岁,范围60 - 75岁)、体重指数(BMI,44.0 ± 6.1)和美国麻醉医师协会(ASA)评分(91%≥ASA 3级)方面相似。术后主要并发症无差异(LSG组3例,4.7%;LRYGB组4例,5.8%;p = 0.75)。中位随访时间为39个月(四分位间距14 - 64个月),无失访患者。接受LRYGB手术的患者在2型糖尿病(DM2)、高血压(HTN)、高脂血症(HL)和胃食管反流病(GERD)方面均有改善,胰岛素使用量显著减少(术前16/47,34.0%;术后7/47,15.2%;p = 0.03)。接受LSG手术的患者DM2和HTN有所改善,但HL和GERD无改善;胰岛素依赖无减少。两组间体重减轻无显著差异;LSG组36个月时平均总体重减轻百分比为26.9 ± 9.0%,LRYGB组为23.9 ± 9.3%,p = 0.24。
LSG和RYGB均可安全地应用于病态肥胖的老年成年人。在中期随访中,老年患者接受LRYGB比LSG有更大的代谢益处。