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经胸神经阻滞可减少儿童起搏器或植入式心脏复律除颤器放置术后的疼痛和阿片类药物的使用。

Pectoral nerve blocks decrease postoperative pain and opioid use after pacemaker or implantable cardioverter-defibrillator placement in children.

机构信息

Department of Pediatrics, Division of Pediatric Cardiology, Stanford University, Stanford, California.

Department of Anesthesiology, Lucile Packard Children's Hospital, Stanford University, Stanford, California.

出版信息

Heart Rhythm. 2020 Aug;17(8):1346-1353. doi: 10.1016/j.hrthm.2020.03.009. Epub 2020 Mar 20.

Abstract

BACKGROUND

Pectoral nerve blocks (PECs) can reduce intraprocedural anesthetic requirements and postoperative pain. Little is known about the utility of PECs in reducing pain and narcotic use after pacemaker (PM) or implantable cardioverter-defibrillator (ICD) placement in children.

OBJECTIVE

The purpose of this study was to determine whether PECs can decrease postoperative pain and opioid use after PM or ICD placement in children.

METHODS

A single-center retrospective review of pediatric patients undergoing transvenous PM or ICD placement between 2015 and 2020 was performed. Patients with recent cardiothoracic surgery or neurologic/developmental deficits were excluded. Demographics, procedural variables, postoperative pain, and postoperative opioid usage were compared between patients who had undergone PECs and those who had undergone conventional local anesthetic (Control).

RESULTS

A total of 74 patients underwent PM or ICD placement; 20 patients (27%) underwent PECs. There were no differences between PECs and Control with regard to age, weight, gender, type of device placed, presence of congenital heart disease, type of anesthesia, procedural time, or complication rates. Patients who underwent PECs had lower pain scores at 1, 2, 6, 18, and 24 hours compared to Control. PECs patients had a lower mean cumulative pain score [PECs 1.5 (95% confidence interval [CI] 0.8-2.2) vs Control 3.1 (95% CI 2.7-3.5); P <.001] and lower total opioid use [PECs 6.0 morphine milligram equivalent (MME)/m (95% CI 3.4-8.6) vs Control 15.0 MME/m (95% CI 11.8-18.2); P = .001] over the 24 hours postimplant.

CONCLUSION

PECs reduce postoperative pain scores and lower total opioid usage after ICD or PM placement. PECs should be considered at the time of transvenous device placement in children.

摘要

背景

胸大肌神经阻滞(PECs)可减少术中麻醉药物的需求和术后疼痛。关于 PEC 在减少儿童起搏器(PM)或植入式心律转复除颤器(ICD)放置术后疼痛和阿片类药物使用方面的作用知之甚少。

目的

本研究旨在确定 PEC 是否可以减少儿童 PM 或 ICD 放置后的术后疼痛和阿片类药物使用。

方法

对 2015 年至 2020 年间接受经静脉 PM 或 ICD 放置的儿科患者进行单中心回顾性研究。排除近期心胸外科手术或神经/发育缺陷的患者。比较行 PEC 与行常规局部麻醉(对照组)的患者的人口统计学、手术变量、术后疼痛和术后阿片类药物使用情况。

结果

共 74 例患者接受 PM 或 ICD 放置;20 例(27%)患者行 PEC。PECs 与对照组在年龄、体重、性别、放置的设备类型、先天性心脏病的存在、麻醉类型、手术时间或并发症发生率方面无差异。与对照组相比,行 PEC 的患者在 1、2、6、18 和 24 小时时疼痛评分较低。PECs 组的平均累积疼痛评分较低[PECs 组 1.5(95%置信区间 [CI] 0.8-2.2)与对照组 3.1(95% CI 2.7-3.5);P <.001],总阿片类药物使用量也较低[PECs 组 6.0 吗啡毫克当量(MME)/m(95% CI 3.4-8.6)与对照组 15.0 MME/m(95% CI 11.8-18.2);P =.001]。

结论

PECs 可降低 ICD 或 PM 放置后的术后疼痛评分和总阿片类药物使用量。在儿童经静脉器械放置时应考虑 PEC。

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