Department of Neurosurgery, Spine and Spinal Cord Institute, College of Medicine, Yonsei University, Seoul, Korea; Department of Neurosurgery, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Department of Neurosurgery, Spine Center, Hallym University Sacred Heart Hospital, Anyang, Korea.
World Neurosurg. 2020 Jun;138:e759-e766. doi: 10.1016/j.wneu.2020.03.071. Epub 2020 Mar 19.
To assess the relationship between frailty, activities of daily living (ADL), instrumental ADL (IADL), and sagittal spinopelvic parameters in the elderly.
To compare the characteristics based on the FRAIL scale status (robust, prefrail, frail), continuous variables were analyzed using ANOVA with Tukey post hoc tests, and categorical variables were analyzed using χ and Fisher's exact test. Multivariate linear regression was used to investigate cross-sectional association between sagittal alignment and FRAIL status.
Comparison analysis of the 3 groups (robust, prefrail, frail) demonstrated that frailty scale had significant correlations with T1 pelvic angle (T1PA, P = 0.019), pelvic tilt (PT, P = 0.004), pelvic incidence minus lumbar lordosis (PI-LL, P = 0.004) and ADL (P = 0.017). Multiple regression analysis that controlled for confounding factors confirmed the correlations between frailty scale and spinopelvic parameters (C7 sagittal vertical axis [SVA], B = 17.49, P = 0.028; T1PA, B = 4.83, P = 0.029; PT, B = 4.62, P = 0.003; PI-LL value, B = 7.11, P = 0.005). In addition, the ADL was associated with T1PA (B = 4.06, P = 0.006); whereas the IADL was correlated with C7 SVA (B = 11.38, P = 0.005), T1PA (B = 3.36, P = 0.003), and PI-LL (B = 3.13, P = 0.018).
Higher frailty score was associated with higher grades of sagittal spinopelvic malalignment and ADL in the elderly. Furthermore, higher ADL and IADL scores were associated with higher grades of sagittal spinopelvic malalignment. Frailty, ADL, IADL, and sagittal spinopelvic parameters were closely related to each other in the elderly.
评估老年人虚弱、日常生活活动(ADL)、工具性日常生活活动(IADL)和矢状脊柱骨盆参数之间的关系。
根据 FRAIL 量表状态(强壮、虚弱前期、虚弱)比较特征,连续变量采用方差分析和 Tukey 事后检验,分类变量采用卡方和 Fisher 确切检验进行分析。采用多元线性回归分析矢状面排列与 FRAIL 状态之间的横断面相关性。
对 3 组(强壮、虚弱前期、虚弱)进行比较分析表明,虚弱量表与 T1 骨盆角(T1PA)、骨盆倾斜度(PT)、骨盆入射角减去腰椎前凸角(PI-LL)和 ADL 有显著相关性(T1PA,P=0.019;PT,P=0.004;PI-LL,P=0.004;ADL,P=0.017)。控制混杂因素的多元回归分析证实了虚弱量表与脊柱骨盆参数之间的相关性(C7 矢状垂直轴[SVA],B=17.49,P=0.028;T1PA,B=4.83,P=0.029;PT,B=4.62,P=0.003;PI-LL 值,B=7.11,P=0.005)。此外,ADL 与 T1PA 相关(B=4.06,P=0.006);而 IADL 与 C7 SVA(B=11.38,P=0.005)、T1PA(B=3.36,P=0.003)和 PI-LL(B=3.13,P=0.018)相关。
虚弱评分越高,老年人矢状面脊柱骨盆失平衡程度越高,ADL 越低。此外,较高的 ADL 和 IADL 评分与较高的矢状面脊柱骨盆失平衡程度相关。老年人中,虚弱、ADL、IADL 和矢状面脊柱骨盆参数之间存在密切关系。