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80 岁以上老年人脊柱病变的手术治疗:叙述性综述。

Surgical management of spinal pathologies in the octogenarian: a narrative review.

机构信息

Department of Neurosurgery, University of Oklahoma, Oklahoma City, OK, USA.

Department of Neurosurgery, Mayo Clinic, Phoenix, AZ, USA.

出版信息

Geroscience. 2024 Aug;46(4):3555-3566. doi: 10.1007/s11357-024-01083-6. Epub 2024 Jan 29.

Abstract

Optimal management paradigms of spinal pathologies in the octogenarian population are controversial given the higher incidence of comorbidities with concern for poor prognosis and fear of increased complications associated with surgical management. In this narrative review, we aim to detail the complex clinical considerations when approaching odontoid screw fixation/instrumented fusion, spinal decompression, and spinal fusion in the octogenarian. Literature review was conducted via Google Scholar and PubMed databases, with literature selected based on statistical power and clinical relevance to the following pathologies/surgical techniques: odontoid fracture, surgical decompression, and surgical fusion in the octogenarian. The aforementioned pathologies were selected based on prevalence in the advanced-age population in which surgical screening techniques and management remain nonuniform. Preoperative evaluation of the octogenarian patient increasingly includes frailty, sarcopenia, and osteopenia/osteoporosis assessments. In cases of odontoid fracture, conservative management appears to provide beneficial clinical outcomes with lower rates of complication compared to surgery; however, rates of radiographic odontoid fusion are far lower in conservatively managed patients. Regarding surgical decompression and fusion, the presence of comorbidities may be more predictive of outcome rather than age status, with the advent of minimally invasive techniques providing safety and efficacy in the surgical management of this age cohort. Age status may be less pertinent than previously thought in the decision to pursue spinal surgery for odontoid fracture, spinal decompression, or spinal fusion; however, each of these procedures has respective risks and benefits that must be considered within the context of each patient's comorbidity profile.

摘要

鉴于高龄人群合并症的发病率较高,对预后的担忧以及对与手术管理相关的并发症增加的恐惧,八十岁以上人群的脊柱病变的最佳治疗模式存在争议。在本篇叙述性综述中,我们旨在详细介绍在处理枢椎螺钉固定/器械融合、脊柱减压和脊柱融合时所涉及的复杂临床考虑因素。文献综述通过 Google Scholar 和 PubMed 数据库进行,文献选择基于统计学效力和与以下病变/手术技术的临床相关性:八十岁以上人群的枢椎骨折、手术减压和手术融合。选择上述病变是基于高龄人群中的患病率,其中手术筛选技术和管理仍然不一致。八十岁以上患者的术前评估越来越多地包括虚弱、肌肉减少症和骨质疏松/骨量减少的评估。对于枢椎骨折,与手术相比,保守治疗似乎提供了有益的临床结果,并且并发症发生率较低;然而,在保守治疗的患者中,影像学上的枢椎融合率要低得多。关于手术减压和融合,合并症的存在可能比年龄状态更能预测结果,微创技术的出现为这一年龄组的手术治疗提供了安全性和有效性。在决定是否进行脊柱手术治疗枢椎骨折、脊柱减压或脊柱融合时,年龄状态可能不如以前认为的那么重要;然而,这些手术各自都有相应的风险和获益,必须根据每个患者的合并症情况进行考虑。

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