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高手术风险老年转子间骨折患者采用带或不带骨水泥强化的股骨近端抗旋髓内钉(PFNA)治疗后恢复至骨折前活动水平的预测因素

Predicting Factors for Return to Prefracture Ambulatory Level in High Surgical Risk Elderly Patients Sustained Intertrochanteric Fracture and Treated With Proximal Femoral Nail Antirotation (PFNA) With and Without Cement Augmentation.

作者信息

Kulachote Noratep, Sa-Ngasoongsong Paphon, Sirisreetreerux Norachart, Chulsomlee Kulapat, Thamyongkit Sorawut, Wongsak Siwadol

机构信息

Department of Orthopedics, Mahidol University, Samut Prakan, Thailand.

Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.

出版信息

Geriatr Orthop Surg Rehabil. 2020 Mar 12;11:2151459320912121. doi: 10.1177/2151459320912121. eCollection 2020.

Abstract

INTRODUCTION

Postoperative outcomes in the elderly patients with intertrochanteric fracture were generally poor with a low rate of return to prefracture ambulatory level (RPAL). Recent studies showed that proximal femoral nail antirotation (PFNA) with cement augmentation might be useful for postoperative functional recovery. This study aimed to compare the outcomes in elderly patients with high surgical risk, American Society of Anesthesiologist (ASA) grade 3 or 4, who sustained intertrochanteric fractures and were treated with PFNA with and without cement augmentation, and to correlate perioperative surgical factors with the RPAL.

METHODS

A retrospective consecutive series was conducted based on 135 patients with prefracture ambulation classified as independent in community with or without a single cane (68 in augmented group and 67 in control group). Perioperative data and data on the complications within 1-year postsurgery were collected and compared. Predictive factors for RPAL were analyzed via logistic regression analysis.

RESULTS

The overall 1-year postoperative mortality rate was 10% (n = 14) with no significant difference between groups ( = .273). The proportion of elderly patients with RPAL in the augmented group was significantly higher than for those in the control group (48% vs 29%, = .043). Via univariate analysis, ASA grade 4 ( = .077), history of stroke ( = .035), and use of cement augmentation ( = .041) were correlated with RPAL. However, multivariate regression analysis showed that ASA grade 4 (odds ratio [OR] = 0.40, 95% confidence interval [CI]: 0.18-0.90, = .026) and use of cement augmentation (OR = 2.72, 95% CI: 1.22-6.05, = .014) were the significant predictors for RPAL.

DISCUSSION AND CONCLUSIONS

The results of the present study showed that PFNA with cement augmentation is safe and effectiveness in the intertrochanteric fracture treatment of elderly. Postoperative functional recovery, like RPAL, in elderly patients who sustained intertrochanteric fractures is relatively low, especially in those with ASA grade 4. However, cement augmentation with PFNA might be helpful for increasing the RPAL in high-surgical-risk geriatric patients.

摘要

引言

老年股骨转子间骨折患者术后预后通常较差,恢复至骨折前活动水平(RPAL)的比例较低。近期研究表明,骨水泥增强型股骨近端抗旋髓内钉(PFNA)可能有助于术后功能恢复。本研究旨在比较手术风险高(美国麻醉医师协会[ASA]3或4级)的老年股骨转子间骨折患者接受有或无骨水泥增强的PFNA治疗后的疗效,并将围手术期手术因素与RPAL进行关联分析。

方法

对135例骨折前可独立行走(有或无单拐)的患者进行回顾性连续系列研究(骨水泥增强组68例,对照组67例)。收集围手术期数据及术后1年内并发症数据并进行比较。通过逻辑回归分析RPAL的预测因素。

结果

术后1年总死亡率为10%(n = 14),两组间无显著差异(P = 0.273)。骨水泥增强组老年患者达到RPAL的比例显著高于对照组(48%对29%,P = 0.043)。单因素分析显示,ASA 4级(P = 0.077)、中风史(P = 0.035)和骨水泥增强的使用(P = 0.041)与RPAL相关。然而,多因素回归分析显示,ASA 4级(比值比[OR] = 0.40,95%置信区间[CI]:0.18 - 0.90,P = 0.026)和骨水泥增强的使用(OR = 2.72,95% CI:1.22 - 6.05,P = 0.014)是RPAL的显著预测因素。

讨论与结论

本研究结果表明,骨水泥增强型PFNA治疗老年股骨转子间骨折安全有效。老年股骨转子间骨折患者术后功能恢复,如RPAL,相对较低,尤其是ASA 4级患者。然而,PFNA联合骨水泥增强可能有助于提高高手术风险老年患者的RPAL。

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