人疱疹病毒6型细胞受体CD134在CD4 + T细胞上的表达与药物性超敏反应综合征/伴嗜酸性粒细胞增多和全身症状的药物反应中Th2型免疫反应的相关性 - Suppr

Suppr

超能文献

Correlation Between Expression of CD134, a Human Herpesvirus 6 Cellular Receptor, on CD4+ T cells and Th2-type Immune Responses in Drug-induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms.

作者信息

Miyagawa Fumi, Nakamura-Nishimura Yuki, Kanatani Yushi, Asada Hideo

机构信息

Department of Dermatology, Nara Medical University Hospital, 840 Shijo, Kashihara, Nara 634-8522, Japan.

出版信息

Acta Derm Venereol. 2020 Mar 31;100(6):adv00102. doi: 10.2340/00015555-3465.

DOI:10.2340/00015555-3465

PMID:32201900

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9128879/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d18/9128879/819e160c97c5/ActaDV-100-6-5724-g001.jpg

相似文献

Correlation Between Expression of CD134, a Human Herpesvirus 6 Cellular Receptor, on CD4+ T cells and Th2-type Immune Responses in Drug-induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms.人疱疹病毒6型细胞受体CD134在CD4 + T细胞上的表达与药物性超敏反应综合征/伴嗜酸性粒细胞增多和全身症状的药物反应中Th2型免疫反应的相关性

Acta Derm Venereol. 2020 Mar 31;100(6):adv00102. doi: 10.2340/00015555-3465.

Preferential expression of CD134, an HHV-6 cellular receptor, on CD4T cells in drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS).HHV-6细胞受体CD134在药物性超敏反应综合征（DIHS）/伴有嗜酸性粒细胞增多和全身症状的药物反应（DRESS）的CD4 T细胞上的优先表达。

J Dermatol Sci. 2016 Aug;83(2):151-4. doi: 10.1016/j.jdermsci.2016.05.001. Epub 2016 May 9.

Skin-Homing IL-13-Producing T Cells Expand in the Circulation of Patients with Drug Rash with Eosinophilia and Systemic Symptoms.皮肤归巢的 IL-13 产生 T 细胞在药物引起的皮疹伴嗜酸性粒细胞增多和全身性症状患者的循环中扩增。

Dermatology. 2017;233(2-3):242-249. doi: 10.1159/000475546. Epub 2017 Jun 10.

OX40/OX40L in systemic lupus erythematosus: association with disease activity and lupus nephritis.系统性红斑狼疮中的OX40/OX40L：与疾病活动及狼疮性肾炎的关联

Ann Saudi Med. 2011 Jan-Feb;31(1):29-34. doi: 10.4103/0256-4947.75775.

The OX40 Axis is Associated with Both Systemic and Local Involvement in Atopic Dermatitis.OX40 轴与特应性皮炎的全身性和局部受累均有关联。

Acta Derm Venereol. 2020 Mar 31;100(6):adv00099. doi: 10.2340/00015555-3452.

Increased expression of human herpes virus 6 receptor CD134/OX40 in skin lesions of patients with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.人疱疹病毒6型受体CD134/OX40在药物性超敏反应综合征/伴有嗜酸性粒细胞增多和全身症状的药物反应患者皮肤病变中的表达增加。

J Dermatol. 2023 Mar;50(3):387-392. doi: 10.1111/1346-8138.16575. Epub 2022 Sep 19.

Elevated serum thymus and activation-regulated chemokine (TARC/CCL17) relates to reactivation of human herpesvirus 6 in drug reaction with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS).血清胸腺和活化调节趋化因子（TARC/CCL17）升高与药物反应伴嗜酸性粒细胞增多和全身症状（DRESS）/药物性超敏反应综合征（DIHS）中人疱疹病毒6的再激活有关。

Br J Dermatol. 2014 Aug;171(2):425-7. doi: 10.1111/bjd.12948. Epub 2014 Aug 2.

Usefulness of rapid measurement of serum thymus and activation-regulated chemokine level in diagnosing drug-induced hypersensitivity syndrome.快速检测血清胸腺和活化调节趋化因子水平在诊断药物性超敏反应综合征中的应用价值

Allergol Int. 2015 Oct;64(4):388-9. doi: 10.1016/j.alit.2015.06.007. Epub 2015 Jul 22.

Differential expression profile of Th1/Th2-associated chemokines characterizes Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) as distinct entities.Th1/Th2相关趋化因子的差异表达谱将史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症（SJS/TEN）和药物性超敏反应综合征/伴嗜酸性粒细胞增多和全身症状的药物反应（DIHS/DRESS）表征为不同的实体。

Eur J Dermatol. 2015 Jan-Feb;25(1):87-9. doi: 10.1684/ejd.2014.2477.

Serum thymus and activation-regulated chemokine is associated with the severity of drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome.血清胸腺和活化调节趋化因子与药物反应伴嗜酸性粒细胞增多和全身症状/药物性超敏反应综合征的严重程度相关。

Br J Dermatol. 2018 Jun;178(6):1430-1432. doi: 10.1111/bjd.16132. Epub 2018 Mar 25.

引用本文的文献

Clinical manifestations, diagnostic criteria, and treatment outcomes of minocycline-associated DRESS syndrome: a comprehensive exploration of published cases.米诺环素相关的药物超敏反应伴嗜酸性粒细胞增多和系统症状（DRESS）综合征的临床表现、诊断标准及治疗结果：已发表病例的综合探究

Front Pharmacol. 2025 Jul 22;16:1515000. doi: 10.3389/fphar.2025.1515000. eCollection 2025.

Exploring recent advances in drugs severe cutaneous adverse reactions immunopathology.探索药物所致严重皮肤不良反应免疫病理学的最新进展。

Allergy. 2025 Jan;80(1):47-62. doi: 10.1111/all.16316. Epub 2024 Sep 18.

The systemic treatments for drug reaction with eosinophilia and systemic symptoms (DRESS) beyond corticosteroids.除皮质类固醇外，药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）的全身治疗方法。

World Allergy Organ J. 2024 Jul 20;17(8):100935. doi: 10.1016/j.waojou.2024.100935. eCollection 2024 Aug.

Advances in understanding of the pathogenesis and therapeutic implications of drug reaction with eosinophilia and systemic symptoms: an updated review.药物超敏反应伴嗜酸性粒细胞增多和全身症状的发病机制及治疗意义的研究进展：最新综述

Front Med (Lausanne). 2023 Jun 29;10:1187937. doi: 10.3389/fmed.2023.1187937. eCollection 2023.

Immunopathogenic Insights on Preferential Human Herpesvirus-6 Reactivation in Drug Rash With Eosinophilia and Systemic Symptoms: A Scoping Review.药物性皮疹伴嗜酸性粒细胞增多和全身症状中人类疱疹病毒 6 优先再激活的免疫发病机制研究：范围综述。

J Cutan Med Surg. 2023 Jul-Aug;27(4):388-398. doi: 10.1177/12034754231177590. Epub 2023 May 25.

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Focus on the Pathophysiological and Diagnostic Role of Viruses.药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）：聚焦病毒在病理生理和诊断中的作用

Microorganisms. 2023 Jan 30;11(2):346. doi: 10.3390/microorganisms11020346.

Chemokines in Severe Cutaneous Adverse Reactions (SCARs).细胞趋化因子在严重皮肤不良反应（SCARs）中的作用。

Biomolecules. 2021 Jun 6;11(6):847. doi: 10.3390/biom11060847.

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity.免疫调节网络在严重药物超敏反应中的作用

Front Immunol. 2021 Feb 26;12:597761. doi: 10.3389/fimmu.2021.597761. eCollection 2021.

Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS).当前对药物诱导的超敏反应综合征/药物伴嗜酸性粒细胞增多和全身症状（DIHS/DRESS）的免疫发病机制的看法。

Int J Mol Sci. 2021 Feb 21;22(4):2147. doi: 10.3390/ijms22042147.

本文引用的文献

Br J Dermatol. 2018 Jun;178(6):1430-1432. doi: 10.1111/bjd.16132. Epub 2018 Mar 25.

J Dermatol Sci. 2016 Aug;83(2):151-4. doi: 10.1016/j.jdermsci.2016.05.001. Epub 2016 May 9.

Eur J Dermatol. 2015 Jan-Feb;25(1):87-9. doi: 10.1684/ejd.2014.2477.

Br J Dermatol. 2014 Aug;171(2):425-7. doi: 10.1111/bjd.12948. Epub 2014 Aug 2.

CD134 is a cellular receptor specific for human herpesvirus-6B entry.CD134 是一种细胞受体，特异性识别人类疱疹病毒-6B 的进入。

Proc Natl Acad Sci U S A. 2013 May 28;110(22):9096-9. doi: 10.1073/pnas.1305187110. Epub 2013 May 14.

Identification of thymus and activation-regulated chemokine (TARC/CCL17) as a potential marker for early indication of disease and prediction of disease activity in drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS).鉴定胸腺激活调节趋化因子（TARC/CCL17）作为药物诱导的超敏反应综合征（DIHS）/伴有嗜酸性粒细胞增多和全身症状的药物疹（DRESS）疾病早期指标和疾病活动预测的潜在标志物。

J Dermatol Sci. 2013 Jan;69(1):38-43. doi: 10.1016/j.jdermsci.2012.10.002. Epub 2012 Oct 26.

The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations.基于典型的临床特征和病毒再激活，DRESS综合征的诊断已得到充分确立。

Br J Dermatol. 2007 May;156(5):1083-4. doi: 10.1111/j.1365-2133.2007.07807.x. Epub 2007 Mar 23.

Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?伴有全身症状的药物皮肤副作用临床模式的变异性：药物超敏反应伴嗜酸性粒细胞增多和系统症状（DRESS）综合征真的存在吗？

Br J Dermatol. 2007 Mar;156(3):609-11. doi: 10.1111/j.1365-2133.2006.07704.x.

Increased levels of interleukin 5 are associated with the generation of eosinophilia in drug-induced hypersensitivity syndrome.白细胞介素5水平升高与药物性超敏反应综合征中嗜酸性粒细胞增多的产生有关。

Br J Dermatol. 1998 Dec;139(6):1026-32. doi: 10.1046/j.1365-2133.1998.02559.x.

OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors.OX40共刺激增强初始阶段白细胞介素-4（IL-4）的表达，并促进人初始CD4(+)T细胞分化为产生高IL-4的效应细胞。

Blood. 1998 Nov 1;92(9):3338-45.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验