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COVID-19:从全球移植角度成功应对大流行。

COVID-19: A global transplant perspective on successfully navigating a pandemic.

机构信息

Transplant Infectious Diseases, Multi-Organ Transplant Program, University Health Network, Toronto, Ontario, Canada.

Infectious Diseases Service and Transplantation Center, Lausanne University Hospital, Lausanne, Switzerland.

出版信息

Am J Transplant. 2020 Jul;20(7):1773-1779. doi: 10.1111/ajt.15876. Epub 2020 Apr 12.

DOI:10.1111/ajt.15876
PMID:32202064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7228301/
Abstract

The COVID-19 pandemic has rapidly evolved and changed our way of life in an unprecedented manner. The emergence of COVID-19 has impacted transplantation worldwide. The impact has not been just restricted to issues pertaining to donors or recipients, but also health-care resource utilization as the intensity of cases in certain jurisdictions exceeds available capacity. Here we provide a personal viewpoint representing different jurisdictions from around the world in order to outline the impact of the current COVID-19 pandemic on organ transplantation. Based on our collective experience, we discuss mitigation strategies such as donor screening, resource planning, and a staged approach to transplant volume considerations as local resource issues demand. We also discuss issues related to transplant-related research during the pandemic, the role of transplant infectious diseases, and the influence of transplant societies for education and disseminating current information.

摘要

COVID-19 大流行以空前的方式迅速发展并改变了我们的生活方式。COVID-19 的出现对全球移植产生了影响。这种影响不仅局限于供体或受体问题,还包括医疗资源的利用,因为某些司法管辖区的病例强度超过了可用能力。在这里,我们提供了来自世界各地不同司法管辖区的个人观点,以概述当前 COVID-19 大流行对器官移植的影响。基于我们的集体经验,我们讨论了缓解策略,例如供体筛查、资源规划以及分阶段考虑移植量的方法,因为当地资源问题需要这样做。我们还讨论了大流行期间与移植相关的研究、移植传染病的作用以及移植学会在教育和传播当前信息方面的影响。

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本文引用的文献

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Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.中国武汉 2019 年冠状病毒病肺炎患者急性呼吸窘迫综合征和死亡的相关危险因素。
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Coronavirus disease 2019: Implications of emerging infections for transplantation.新型冠状病毒病 2019:新发感染对移植的影响。
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Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury.临床证据不支持使用皮质类固醇治疗2019新型冠状病毒肺炎肺损伤。
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Zika Virus in Transplantation: Emerging Infection and Opportunities.移植中的寨卡病毒:新出现的感染与机遇
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Ebola virus disease: implications for solid organ transplantation.埃博拉病毒病:对实体器官移植的影响
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Am J Transplant. 2014 May;14(5):1003-11. doi: 10.1111/ajt.12666. Epub 2014 Mar 17.
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Pandemic influenza and its implications for transplantation.大流行性流感及其对移植的影响。
Am J Transplant. 2006 Jul;6(7):1512-7. doi: 10.1111/j.1600-6143.2006.01364.x.
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Emerging viral infections in transplant recipients.移植受者中的新发病毒感染
Curr Opin Infect Dis. 2005 Aug;18(4):337-41. doi: 10.1097/01.qco.0000172697.44784.ff.
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Severe Acute Respiratory Syndrome (SARS) in a liver transplant recipient and guidelines for donor SARS screening.一名肝移植受者的严重急性呼吸综合征(SARS)及供体SARS筛查指南
Am J Transplant. 2003 Aug;3(8):977-81. doi: 10.1034/j.1600-6143.2003.00197.x.