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无缺血性坏死受试者心肌和主动脉组织中镁水平的研究(作者译)

[Study of magnesium level in myocardium and aorta tissues from subjects free of ishemic necrosis (author's transl)].

作者信息

Speich M, Mainard F, Nicolas G, Bousquet B

出版信息

Pathol Biol (Paris). 1977 Feb;25(2):101-4.

PMID:322040
Abstract

Before carrying out a study on the levels of magnesium in the myocardium and the aorta in subjects who had died of coronary thrombosis, we determined the reference levels of magnesium in the right and left ventricles and in the aorta of sixteen normal subjects. The samples were homogenized and digested with nitric acid/hydrochloric acid mixture before the measurement itself was made; this was carried out by atomic absorption spectrophotometry. The magnesium values are expressed in microng/g of wet tissue, in mg/g of tissular proteins, in mg/ of total lipids in the aortic wall. The differences between the concentrations of proteins or magnesium in the left and right ventricles are significant magnesium in the left and right ventricles are significant (P less than 0,001). They probably derive from anatomic and physiological differences. We have found a correlation which is significantly positive between magnesium level and protein level in the ventricle. In the aorta, the results for proteins, lipids and magnesium are extremely dispersed because of the heterogeneous nature of biochemical composition of this tissue according to age and area which it has been taken from.

摘要

在对死于冠状动脉血栓形成的受试者的心肌和主动脉中的镁水平进行研究之前,我们测定了16名正常受试者右心室、左心室和主动脉中的镁参考水平。在进行测量之前,将样本匀浆并用硝酸/盐酸混合物消化;这通过原子吸收分光光度法进行。镁值以微克/克湿组织、毫克/克组织蛋白、毫克/主动脉壁总脂质表示。左心室和右心室中蛋白质或镁浓度之间的差异显著(P小于0.001)。它们可能源于解剖学和生理学差异。我们发现心室中镁水平与蛋白质水平之间存在显著的正相关。在主动脉中,由于该组织的生化组成根据其取自的年龄和区域而异质,蛋白质、脂质和镁的结果极为分散。

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