Bossù Maurizio, Iaculli Flavia, Di Giorgio Gianni, Salucci Alessandro, Polimeni Antonella, Di Carlo Stefano
Department of Oral and Maxillofacial Science, "Sapienza" University of Rome, 00185 Rome, Italy.
Pediatric Dentistry School, Department of Oral and Maxillofacial Science, "Sapienza" University of Rome, 00185 Rome, Italy.
J Clin Med. 2020 Mar 19;9(3):838. doi: 10.3390/jcm9030838.
: Pulpotomy of primary teeth provides favorable clinical results over time; however, to date, there is still not a consensus on an ideal pulp dressing material. Therefore, the aim of the present systematic review was to compare pulpotomy agents to establish a preferred material to use. : After raising a PICO question, the PRISMA guideline was adopted to carry out an electronic search through the MEDLINE database to identify comparative studies on several pulp dressing agents, published up to October 2019. : The search resulted in 4274 records; after exclusion, a total of 41 papers were included in the present review. Mineral trioxide aggregate (MTA), Biodentine and ferric sulphate yielded good clinical results over time and might be safely used in the pulpotomies of primary molars. Among agents, MTA seemed to be the material of choice. On the contrary, calcium hydroxide showed the worst clinical performance. Although clinically successful, formocreosol should be replaced by other materials, due to its potential cytotoxicity and carcinogenicity. : MTA seemed to be the gold standard material in the pulpotomy of primary teeth. Promising results were also provided by calcium silicate-based cements. Further randomized clinical trials (RCTs) with adequate sample sizes and long follow-ups are encouraged to support these outcomes.
乳牙活髓切断术长期以来能带来良好的临床效果；然而，迄今为止，对于理想的牙髓盖髓材料仍未达成共识。因此，本系统评价的目的是比较活髓切断术所用药物，以确定首选材料。：提出PICO问题后，采用PRISMA指南通过MEDLINE数据库进行电子检索，以识别截至2019年10月发表的关于几种牙髓盖髓剂的比较研究。：检索结果为4274条记录；排除后，本评价共纳入41篇论文。随着时间推移，矿物三氧化物凝聚体（MTA）、生物活性玻璃粘固粉和硫酸铁产生了良好的临床效果，可安全用于乳牙磨牙的活髓切断术。在这些药物中，MTA似乎是首选材料。相反，氢氧化钙的临床性能最差。甲醛甲酚虽然临床成功，但因其潜在的细胞毒性和致癌性，应被其他材料取代。：MTA似乎是乳牙活髓切断术的金标准材料。硅酸钙基水门汀也取得了有前景的结果。鼓励开展更多样本量充足且随访时间长的随机临床试验（RCT）来支持这些结果。
