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TheraCal与甲醛甲酚用于乳牙牙髓切断术的临床及影像学成功率:一项系统评价与分析

Clinical and radiographic success of TheraCal versus Formocresol in primary teeth pulpotomy: A systematic review and -analysis.

作者信息

Amrollahi Narjes, Karimi Rahele, Shariati Faezeh

机构信息

Dental Research Center, Department of Pediatric Dentistry, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Saudi Dent J. 2024 Aug;36(8):1058-1065. doi: 10.1016/j.sdentj.2024.06.008. Epub 2024 Jun 6.

DOI:10.1016/j.sdentj.2024.06.008
PMID:39176161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11337966/
Abstract

BACKGROUND

Various dressing materials have been evaluated for pulpotomy of primary teeth. However, an ideal pulp dressing material has not been identified yet. This systematic review investigated the effectiveness of TheraCal compared to Formocresol in pulpotomy of primary teeth.

MATERIALS AND METHODS

This research was conducted in the form of a secondary study, with a systematic search of texts until 2023 in Scopus, Web of Science, PubMed and Google Scholar databases. The articles were selected based on the inclusion and exclusion criteria and, finally the search results were reported in the PRISMA chart. The quality of the studies was evaluated based on the NIH checklist. The extracted information was entered into Stata17 software. Heterogeneity was evaluated using Cochran's chi-square test and I statistics. Egger's tests were used to detect publication bias

RESULTS

After removing duplicate articles and articles that did not meet the inclusion criteria, 4 studies were selected for qualitative analysis. The odds' ratio of success rate between Formocresol and TheraCal pulpotomy for absence of the pain, abscess, Mobility, internal root resorption and bone radiolucency was obtained 1.12 (95 % CI: 0.32, 3.85, P = 0.86), 0.47 (95 % CI: 0.1, 2.14, P = 0.33), 0.82 (95 % CI: 0.21, 3.21, P = 0.78), 0.89 (95 % CI: 0.3, 2.67, P = 0.84), and 1.96 (95 % CI: 0.68, 5.62, P = 0.21) respectively.

CONCLUSION

The study results revealed that there was no significant difference in clinical and radiographic success between pulpotomy with TheraCal and Formocresol.

摘要

背景

已对多种用于乳牙牙髓切断术的敷料材料进行了评估。然而,尚未确定理想的牙髓敷料材料。本系统评价研究了与甲醛甲酚相比,TheraCal在乳牙牙髓切断术中的有效性。

材料与方法

本研究以二次研究的形式进行,在Scopus、Web of Science、PubMed和谷歌学术数据库中系统检索截至2023年的文献。根据纳入和排除标准选择文章,最后在PRISMA图中报告检索结果。根据美国国立卫生研究院(NIH)清单评估研究质量。将提取的信息录入Stata17软件。使用Cochran卡方检验和I统计量评估异质性。使用Egger检验检测发表偏倚。

结果

在去除重复文章和不符合纳入标准的文章后,选择了4项研究进行定性分析。甲醛甲酚和TheraCal牙髓切断术在无疼痛、脓肿、松动、牙根内吸收和骨透射区方面成功率的比值比分别为1.12(95%可信区间:0.32,3.85,P = 0.86)、0.47(95%可信区间:0.1,2.14,P = 0.33)、0.82(95%可信区间:0.21,3.21,P = 0.78)、0.89(95%可信区间:0.3,2.67,P = 0.84)和1.96(95%可信区间:0.68,5.62,P = 0.21)。

结论

研究结果表明,TheraCal和甲醛甲酚牙髓切断术在临床和影像学成功率方面无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ea6/11337966/8e55da7ed9b3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ea6/11337966/8e55da7ed9b3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ea6/11337966/8e55da7ed9b3/gr1.jpg

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本文引用的文献

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Clin Oral Investig. 2023 Jan;27(1):91-104. doi: 10.1007/s00784-022-04830-1. Epub 2022 Dec 29.
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LIGHT-CURED CALCIUM SILICATE BASED-CEMENTS AS PULP THERAPEUTIC AGENTS: A META-ANALYSIS OF CLINICAL STUDIES.基于光固化硅酸钙的牙髓治疗剂:临床研究的荟萃分析
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Comparative Evaluation of the Efficacy of Light-Cured Calcium Hydroxide and a Fourth-Generation Calcium Silicate Cement (TheraCal LC) as Indirect Pulp Capping Materials in Patients With Deep Carious Lesions: A Randomized Parallel-Group Clinical Trial.
光固化氢氧化钙与第四代硅酸钙水门汀(TheraCal LC)作为深龋病变患者间接盖髓材料疗效的比较评价:一项随机平行组临床试验
Cureus. 2022 Sep 7;14(9):e28882. doi: 10.7759/cureus.28882. eCollection 2022 Sep.
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An Update on Newer Pulpotomy Agents in Primary Teeth: A Literature Review.乳牙新型牙髓切断术药物的最新进展:文献综述
J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S57-S61. doi: 10.4103/jpbs.JPBS_799_20. Epub 2021 Jun 5.
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Efficacy of different calcium silicate materials as pulp-capping agents: Randomized clinical trial.不同硅酸钙材料作为盖髓剂的疗效:随机临床试验。
J Dent Sci. 2021 Mar;16(2):723-731. doi: 10.1016/j.jds.2020.08.016. Epub 2020 Sep 17.
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Clinical, radiographic, and histological evaluation of three different pulp-capping materials in indirect pulp treatment of primary teeth: a randomized clinical trial.临床、放射学和组织学评价三种不同盖髓材料在乳前牙间接盖髓治疗中的应用:一项随机临床试验。
Clin Oral Investig. 2021 Jun;25(6):3945-3955. doi: 10.1007/s00784-020-03724-4. Epub 2021 Jan 6.
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