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采用改良腭瓣技术矫正阻塞性睡眠呼吸暂停(OSA)患者的获得性鼻咽狭窄。

Acquired Nasopharyngeal Stenosis Correction Using a Modified Palatal Flaps Technique in Obstructive Sleep Apnea (OSA) Patients.

机构信息

Head and Neck Department, ENT & Oral Surgery Unit, G.B. Morgagni, L. Pierantoni Hospital, 47100 Forlì, Italy.

Department of Otolaryngology, University of Messina, 98100 Messina, Italy.

出版信息

Int J Environ Res Public Health. 2020 Mar 19;17(6):2048. doi: 10.3390/ijerph17062048.

DOI:10.3390/ijerph17062048
PMID:32204516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7142903/
Abstract

: Acquired nasopharyngeal stenosis is a rare and heterogeneous pathological condition that has different causes, generally resulting as a complication of a pharyngeal surgery, especially in patients affected by obstructive sleep apnea (OSA). Different approaches have been proposed for the treatment of nasopharyngeal stenosis but a unique and standardized management has not yet been presented. The aim of our paper is to evaluate the efficacy of our surgical technique, describing its steps and results with the aim to consider it as a possible solution for the treatment of this condition. : This is a retrospective cohort study. Eight patients (mean age 27.25 years old (yo), range 8-67 yo; Male/Female ratio 4/4; mean body mass index (BMI) 26.1) affected by OSA (mean apnea hypopnea index (AHI) before OSA surgery was 22.1) and acquired nasopharyngeal stenosis as a consequence of different pharyngeal surgeries were treated with our modified approach in the Department of Otolaryngology, Morgagni Pierantoni Hospital, Forlì, Italy. Resolution of stenosis and complication rate were the main outcome measures. : Complete resolution of the stenosis was achieved in all cases and no complications were recorded at three weeks, six months, and 2 years follow-up. : Our technique appears to be a promising method for the management of nasopharyngeal stenosis in OSA patients. However, further studies comparing different techniques and reporting on larger series and longer follow up time are needed to prove the efficacy of the proposed technique.

摘要

后天性鼻咽狭窄是一种罕见且异质性的病理状况,具有不同的病因,通常是咽手术的并发症,尤其是在阻塞性睡眠呼吸暂停(OSA)患者中。对于鼻咽狭窄的治疗已经提出了不同的方法,但尚未提出独特和标准化的管理方法。我们的目的是评估我们的手术技术的疗效,描述其步骤和结果,以期将其视为治疗这种疾病的一种可能方法。

这是一项回顾性队列研究。意大利福里莫尔加尼·皮耶朗托尼医院耳鼻喉科收治了 8 例 OSA 患者(平均年龄 27.25 岁,年龄 8-67 岁;男/女比例 4/4;平均体重指数(BMI)26.1),因不同的咽手术而患有后天性鼻咽狭窄。我们采用改良方法治疗。主要结局指标为狭窄的缓解率和并发症发生率。

所有患者的狭窄均完全缓解,在 3 周、6 个月和 2 年随访时均未发生并发症。

我们的技术似乎是 OSA 患者治疗鼻咽狭窄的一种很有前途的方法。然而,需要进一步的研究来比较不同的技术,并报告更大的系列和更长的随访时间,以证明所提出的技术的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/341138cd4f3b/ijerph-17-02048-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/3839b784c9e9/ijerph-17-02048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/36c36f62ac1b/ijerph-17-02048-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/341138cd4f3b/ijerph-17-02048-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/3839b784c9e9/ijerph-17-02048-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/36c36f62ac1b/ijerph-17-02048-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ce/7142903/341138cd4f3b/ijerph-17-02048-g003.jpg

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