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Channelopathy of the Pancreas Causes Chronic Pancreatitis.

作者信息

Sahin-Tóth Miklós

机构信息

Department of Surgery, University of California Los Angeles, Los Angeles, California.

出版信息

Gastroenterology. 2020 May;158(6):1538-1540. doi: 10.1053/j.gastro.2020.03.027. Epub 2020 Mar 20.

DOI:10.1053/j.gastro.2020.03.027
PMID:32205170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7751598/
Abstract
摘要

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[Liver condition in chronic pancreatitis; an attempt to establish a physiopathological unity between pancreas and liver].[慢性胰腺炎中的肝脏状况；尝试建立胰腺与肝脏之间的生理病理统一性]
Rev Int Hepatol. 1955;5(6):745-60.
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Pancreas and liver injury are associated in individuals with increased alcohol consumption.过量饮酒会导致个体的胰腺和肝脏损伤。
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[Contribution to the study of the relations between chronic pancreatitis and liver insufficiency in patients with posthepatitis cirrhosis].[对肝炎后肝硬化患者慢性胰腺炎与肝功能不全关系的研究贡献]
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Structure and function of the calcium-selective TRP channel TRPV6.钙选择性 TRP 通道 TRPV6 的结构与功能。
J Physiol. 2021 May;599(10):2673-2697. doi: 10.1113/JP279024. Epub 2020 Mar 13.
2
Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis.影响钙通道 TRPV6 功能的变异与早发性慢性胰腺炎有关。
Gastroenterology. 2020 May;158(6):1626-1641.e8. doi: 10.1053/j.gastro.2020.01.005. Epub 2020 Jan 10.
3
TRPV6 as A Target for Cancer Therapy.瞬时受体电位香草酸亚型6作为癌症治疗的靶点
急性和慢性胰腺炎的研究进展。
World J Gastroenterol. 2023 Feb 21;29(7):1194-1201. doi: 10.3748/wjg.v29.i7.1194.
4
A novel frameshift mutation in is associated with hereditary pancreatitis.某基因中的一种新型移码突变与遗传性胰腺炎相关。
Front Genet. 2023 Jan 9;13:1058057. doi: 10.3389/fgene.2022.1058057. eCollection 2022.
5
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice.CEL-HYB1 基因风险因素可导致小鼠发生蛋白质毒性和慢性胰腺炎。
Pancreatology. 2022 Dec;22(8):1099-1111. doi: 10.1016/j.pan.2022.11.003. Epub 2022 Nov 9.
6
What structures did, and did not, reveal about the function of the epithelial Ca channels TRPV5 and TRPV6.这些结构揭示了上皮钙通道 TRPV5 和 TRPV6 的哪些功能，又没有揭示哪些功能。
Cell Calcium. 2022 Sep;106:102620. doi: 10.1016/j.ceca.2022.102620. Epub 2022 Jul 3.
7
Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort.常见钙敏感受体 (CASR) 基因变异不会改变匈牙利队列慢性胰腺炎的风险。
Pancreatology. 2021 Oct;21(7):1305-1310. doi: 10.1016/j.pan.2021.08.012. Epub 2021 Aug 26.
8
Genetic Risk Factors in Early-Onset Nonalcoholic Chronic Pancreatitis: An Update.早发性非酒精性慢性胰腺炎的遗传风险因素：最新研究进展。
Genes (Basel). 2021 May 20;12(5):785. doi: 10.3390/genes12050785.
J Cancer. 2020 Jan 1;11(2):374-387. doi: 10.7150/jca.31640. eCollection 2020.
4
Gene Mutation in a Dizygous Twin With Transient Neonatal Hyperparathyroidism.双卵双胎之一患短暂性新生儿甲状旁腺功能亢进症的基因突变
J Endocr Soc. 2019 Jan 3;3(3):602-606. doi: 10.1210/js.2018-00374. eCollection 2019 Mar 1.
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Gastroenterology. 2019 May;156(7):1951-1968.e1. doi: 10.1053/j.gastro.2018.11.081. Epub 2019 Jan 18.
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TRPV6 compound heterozygous variants result in impaired placental calcium transport and severe undermineralization and dysplasia of the fetal skeleton.瞬时受体电位香草酸亚型6（TRPV6）复合杂合变异导致胎盘钙转运受损以及胎儿骨骼严重矿化不足和发育异常。
Am J Med Genet A. 2018 Sep;176(9):1950-1955. doi: 10.1002/ajmg.a.40484. Epub 2018 Aug 25.
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TRPV6 Variants Interfere with Maternal-Fetal Calcium Transport through the Placenta and Cause Transient Neonatal Hyperparathyroidism.TRPV6 变体通过胎盘干扰母体-胎儿钙转运并导致短暂性新生儿甲状旁腺功能亢进症。
Am J Hum Genet. 2018 Jun 7;102(6):1104-1114. doi: 10.1016/j.ajhg.2018.04.006. Epub 2018 May 31.
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Dig Dis Sci. 2017 Jul;62(7):1692-1701. doi: 10.1007/s10620-017-4601-3. Epub 2017 May 23.
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TRPV6: From identification to function.瞬时受体电位香草酸亚型6：从发现到功能研究
Cell Calcium. 2017 Nov;67:116-122. doi: 10.1016/j.ceca.2017.04.006. Epub 2017 Apr 28.