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成人多发性硬化症专科住院康复的成本效益:对英国康复结果协作组织英格兰康复中心国家临床数据集的多中心前瞻性队列分析。

Cost-efficiency of specialist inpatient rehabilitation for adults with multiple sclerosis: A multicentre prospective cohort analysis of the UK Rehabilitation Outcomes Collaborative national clinical dataset for rehabilitation centres in England.

作者信息

Turner-Stokes Lynne, Harding Richard, Yu Peihan, Dzingina Mendwas, Gao Wei

机构信息

Department of Palliative Care, Policy and Rehabilitation, Faculty of Nursing Midwifery and Palliative Care, King's College London, UK.

出版信息

Mult Scler J Exp Transl Clin. 2020 Mar 16;6(1):2055217320912789. doi: 10.1177/2055217320912789. eCollection 2020 Jan-Mar.

DOI:10.1177/2055217320912789
PMID:32206333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7079310/
Abstract

BACKGROUND

Rehabilitation is effective for multiple sclerosis, but is it value for money?

OBJECTIVES

To evaluate functional outcomes, care needs and cost-efficiency of specialist inpatient rehabilitation for adults with multiple sclerosis (MS).

METHODS

A multicentre cohort study of prospectively collected clinical data from the UK Rehabilitation Outcomes Collaborative national clinical database. Data included all adults with MS ( = 1007) admitted for specialist inpatient (Level 1 or 2) rehabilitation in England, 2010-2018.

OUTCOME MEASURES

Dependency/care needs: Northwick Park Dependency Scale/Care Needs Assessment, Functional independence: UK Functional Assessment Measure (UK FIM+FAM). Cost-efficiency. Patients were analysed in three dependency groups (High/Medium/Low).

RESULTS

All groups showed significant reduction in dependency between admission and discharge on all measures (paired -tests:  < 0.001). Mean reduction in care costs/week was greatest in the most dependent patients: High: £519 (95% CI: 447-597), Medium: £148 (76-217), Low: £36 (12-83). Despite longer stays, time taken to offset the cost of rehabilitation was shortest in the most dependent patients: High: 12.9 (12.0-14.1) months; Medium: 29.3 (21.3-51.8); Low: 76.8 (0-36.1). Item-level changes corresponded with clinical experience.

CONCLUSIONS

Specialist rehabilitation provided good value for money in patients with MS, yielding improved outcomes and substantial savings in ongoing care costs, especially in high-dependency patients.

摘要

背景

康复治疗对多发性硬化症有效,但它是否物有所值?

目的

评估成年多发性硬化症(MS)患者专科住院康复治疗的功能结局、护理需求和成本效益。

方法

一项多中心队列研究,前瞻性收集来自英国康复结局协作组织国家临床数据库的临床数据。数据包括2010年至2018年在英格兰因专科住院(1级或2级)康复治疗而入院的所有成年MS患者(n = 1007)。

结局指标

依赖性/护理需求:诺斯威克公园依赖性量表/护理需求评估,功能独立性:英国功能评估量表(UK FIM+FAM)。成本效益。患者被分为三个依赖性组(高/中/低)进行分析。

结果

所有组在所有指标上入院时和出院时的依赖性均显著降低(配对t检验:p < 0.001)。护理成本/周的平均降低幅度在依赖性最强的患者中最大:高:519英镑(95%CI:447 - 597),中:148英镑(76 - 217),低:36英镑(12 - 83)。尽管住院时间较长,但抵消康复治疗成本所需时间在依赖性最强的患者中最短:高:12.9(12.0 - 14.1)个月;中:29.3(21.3 - 51.8);低:76.8(0 - 36.1)。项目层面的变化与临床经验相符。

结论

专科康复治疗对MS患者具有良好的成本效益,可改善结局并大幅节省持续护理成本,尤其是在高依赖性患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/17a5a9d8c421/10.1177_2055217320912789-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/90407adeb828/10.1177_2055217320912789-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/e68e860f2390/10.1177_2055217320912789-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/17a5a9d8c421/10.1177_2055217320912789-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/90407adeb828/10.1177_2055217320912789-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/e68e860f2390/10.1177_2055217320912789-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ae6/7079310/17a5a9d8c421/10.1177_2055217320912789-fig3.jpg

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The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial.
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