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一例罕见的肺炎克雷伯菌心内膜炎病例。

An Unusual Case of Klebsiella pneumoniae Endocarditis.

作者信息

Hassan Syed Adeel, Akhtar Ali, Falah Noor Ul, Khan Maham

机构信息

Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Internal Medicine, Army Medical College, National University of Medical Sciences, Rawalpindi, PAK.

出版信息

Cureus. 2020 Feb 14;12(2):e6999. doi: 10.7759/cureus.6999.

Abstract

Klebsiella pneumoniae notoriously causes life-threatening community-acquired or hospital-acquired pneumonia. In the United States, community-acquired pneumonia is a relatively common diagnosis. However, community-acquired pneumonia due to Klebsiella pneumoniae is fairly uncommon. Delayed antibiotic administration can result in bacteremia, septicemia and other systemic complications. Infective endocarditis arising as a complication of community-acquired Klebsiella pneumoniae infection has rarely been reported. Our patient is an 88-year-old diabetic female, who was admitted to our intensive care unit due to a high-grade fever, worsening dyspnea and hypotension. Chest x-ray and blood culture were conclusive for pneumonia due to Klebsiella pneumoniae. Importantly, the species was only susceptible to colistin. Furthermore, an echocardiogram revealed mobile vegetations of the non-coronary cusp of the aortic valve. Treatment with colistin resulted in clinical improvement and an uneventful discharge from the hospital. Follow up echocardiography was scheduled upon discharge to monitor the resolution of cardiac vegetations.

摘要

肺炎克雷伯菌是出了名的会引发危及生命的社区获得性或医院获得性肺炎。在美国,社区获得性肺炎是一种相对常见的诊断。然而,由肺炎克雷伯菌引起的社区获得性肺炎相当罕见。抗生素使用延迟可导致菌血症、败血症及其他全身并发症。作为社区获得性肺炎克雷伯菌感染并发症出现的感染性心内膜炎鲜有报道。我们的患者是一名88岁的糖尿病女性,因高热、呼吸困难加重和低血压入住我们的重症监护病房。胸部X光和血培养确诊为肺炎克雷伯菌所致肺炎。重要的是,该菌株仅对黏菌素敏感。此外,超声心动图显示主动脉瓣无冠瓣有活动的赘生物。使用黏菌素治疗后临床症状改善,患者顺利出院。出院时安排了超声心动图随访以监测心脏赘生物的消退情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63bf/7077065/36f485b3a399/cureus-0012-00000006999-i01.jpg

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