K2 血清型肺炎克雷伯菌引起肝脓肿合并感染性心内膜炎。
K2 serotype Klebsiella pneumoniae causing a liver abscess associated with infective endocarditis.
机构信息
Division of Infectious Diseases, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
出版信息
J Clin Microbiol. 2010 Feb;48(2):639-41. doi: 10.1128/JCM.01779-09. Epub 2009 Dec 9.
Abstract
Klebsiella pneumoniae primary liver abscess (KPLA) is an emerging disease that is associated with distant septic complications. We report the first case of KPLA associated with infective endocarditis. The K. pneumoniae strain was a hypermucoid K2 serotype carrying the rmpA virulence-associated gene.
摘要
肺炎克雷伯菌原发性肝脓肿（KPLA）是一种新兴疾病，与远处脓毒症并发症有关。我们报告首例与感染性心内膜炎相关的 KPLA 病例。肺炎克雷伯菌菌株为携带 rmpA 毒力相关基因的高粘液型 K2 血清型。
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2
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J Microbiol Immunol Infect. 2008 Aug;41(4):311-7.
3
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J Infect Dis. 2007 Apr 15;195(8):1235-6; author reply 1236. doi: 10.1086/512686.
4
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