Kamburoğlu Kıvanç, Ereş Gülden, Akgün Ceren
Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara, Turkey.
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey.
J Vet Dent. 2019 Dec;36(4):245-250. doi: 10.1177/0898756420911108.
Cone-beam computed tomography (CBCT) has strong potential to be utilized in various aspects of veterinary dentistry. Using ex vivo rat maxillary bone and teeth, the purpose of this study was to compare gray value, surface area, and volumetric measurements of teeth with and without experimental periodontitis by CBCT. Periodontitis was induced in 36 molar teeth, while 36 teeth with a healthy periodontium served as control. Images of each specimen along with teeth were obtained using CBCT. The following measurements for each tooth with periodontitis (n = 36) were recorded: gray value measurement, width, height, depth, surface area, and volume of the alveolar bone loss. For the control group (n = 36), gray value measurement, surface area, and volume of the alveolar bone were recorded. All measurements were repeated after 3 weeks. As the gold standard, the rat maxillas were decalcified and paraffin-embedded for further immunocytochemical study. One-way analysis of variance (ANOVA) was used. Significance level was set at < .05. Correlation values for gray value, width, height, depth, surface area, and volume measurements were 0.983, 0.966, 0.962, 0.880, 0.998, and 0.999, respectively, for the first and second measurements. One way ANOVA showed statistically significant differences between teeth with and without alveolar bone destruction conducted for gray value, surface area, and volume measurements ( = .000). Mean gray value, surface area, and volume measurements decreased 56.46%, 81.89%, and 78.56%, respectively, for teeth with alveolar bone destruction in comparison to healthy teeth. Cone-beam computed tomography provided useful qualitative and quantitative information regarding induced periodontitis in the rat maxilla.
锥形束计算机断层扫描（CBCT）在兽医牙科的各个方面具有很强的应用潜力。本研究以大鼠离体上颌骨和牙齿为研究对象，旨在通过CBCT比较有或无实验性牙周炎的牙齿的灰度值、表面积和体积测量值。对36颗磨牙诱导牙周炎，36颗牙周健康的牙齿作为对照。使用CBCT获取每个标本及其牙齿的图像。记录每颗患有牙周炎的牙齿（n = 36）的以下测量值：灰度值测量、牙槽骨丧失的宽度、高度、深度、表面积和体积。对于对照组（n = 36），记录牙槽骨的灰度值测量、表面积和体积。3周后重复所有测量。作为金标准，将大鼠上颌骨脱钙并石蜡包埋用于进一步的免疫细胞化学研究。采用单因素方差分析（ANOVA）。显著性水平设定为<0.05。第一次和第二次测量的灰度值、宽度、高度、深度、表面积和体积测量的相关值分别为0.983、0.966、0.962、0.880、0.998和0.999。单因素方差分析显示，在进行灰度值、表面积和体积测量时，有或无牙槽骨破坏的牙齿之间存在统计学显著差异（P = 0.000）。与健康牙齿相比，牙槽骨破坏的牙齿的平均灰度值、表面积和体积测量值分别下降了56.46%、81.89%和78.56%。锥形束计算机断层扫描提供了有关大鼠上颌骨诱导性牙周炎的有用定性和定量信息。
