妊娠合并恰加斯病：苯达唑对妊娠和新生儿的影响：4 例报告。
Pregnancy and Chagas Disease: Benznidazole's Impact on Pregnancy and Newborns: A Report of Four Cases.
机构信息
Unidad de Medicina Tropical, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
Universidad de Murcia, Murcia, Spain.
出版信息
Am J Trop Med Hyg. 2020 May;102(5):1075-1077. doi: 10.4269/ajtmh.19-0348.
Abstract
In recent decades and because of migration, Chagas disease has become a global public health problem. A significant focus has been placed on pregnant women who can transmit the disease to their offspring. Here, we report four cases of women who did not know that they were pregnant while they were being treated with benznidazole. A diagnosis was established according to serology and polymerase chain reaction (PCR)-standardized tests. Treatment was discontinued when pregnancy was confirmed, and a thorough follow-up was carried out. Although each case was different, none of the mothers developed health problems during pregnancy, and their newborns were delivered without any teratogenic effects.
摘要
近几十年来，由于移民，恰加斯病已成为一个全球性的公共卫生问题。人们高度关注可以将该病传染给后代的孕妇。在这里，我们报告了四例正在接受苯达唑治疗而不知道自己怀孕的女性病例。根据血清学和聚合酶链反应（PCR）标准化检测结果做出了诊断。当确认怀孕时，停止了治疗，并进行了彻底的随访。尽管每个病例都不同，但没有一位母亲在怀孕期间出现健康问题，她们的新生儿也没有出现任何致畸作用。
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