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对感染克氏锥虫的年轻女性进行病因治疗,并预防先天性传播。

Etiological treatment of young women infected with Trypanosoma cruzi, and prevention of congenital transmission.

机构信息

Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias, Administración Nacional de Laboratorios, Buenos Aires, Argentina.

出版信息

Rev Soc Bras Med Trop. 2009 Sep-Oct;42(5):484-7. doi: 10.1590/s0037-86822009000500002.

Abstract

The objective was to detect Trypanosoma cruzi infection in 32 children in Salta, Argentina, born to 16 chronically infected young women who were treated with benznidazole. Tests were performed to assess the efficacy of treatment after 14 years. At the end of the follow up, 87.5% of the women were non-reactive to EIA tests, 62.5% to IHA and 43.8% to IFA. 62.5% of the women were non-reactive according to two or three serological tests. No infected children were detected among the newborns of mothers treated before their pregnancy.

摘要

目的是在阿根廷萨尔塔检测 32 名儿童是否感染克氏锥虫,这些儿童均为 16 名接受苯并咪唑治疗的慢性感染年轻女性所生。检测在 14 年后进行,以评估治疗效果。在随访结束时,87.5%的女性对 EIA 检测无反应,62.5%对 IHA 检测无反应,43.8%对 IFA 检测无反应。根据两种或三种血清学检测结果,62.5%的女性无反应。在母亲在怀孕前接受治疗的新生儿中,没有检测到感染的儿童。

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