Stöberl C, Partsch H
Dermatologische Abteilung, KA-Rudolfstiftung Wien.
Hautarzt. 1988 Jul;39(7):441-6.
In seven patients with papillomatosis cutis in chronically congested lower extremities (lymphoedema, chronic venous insufficiency, chronic cardiac insufficiency) indirect lymphography revealed abnormalities of dermal lymph drainage. In four of these patients punch biopsies were taken from the papillomas. Microscopic examination revealed hyperplasia of the epidermis and dilated capillary-like vessels. Papillomatosis cutis in chronically congested lower extremities can be distinguished from pseudoepitheliomatose and carcinomatose alterations by both clinical and histological examination. Impaired local lymph transport seems to be the decisive trigger mechanism for the development of these papillomas.
在7例慢性充血性下肢（淋巴水肿、慢性静脉功能不全、慢性心功能不全）皮肤乳头瘤病患者中，间接淋巴管造影显示真皮淋巴引流异常。其中4例患者的乳头瘤进行了钻孔活检。显微镜检查显示表皮增生和扩张的毛细血管样血管。通过临床和组织学检查，慢性充血性下肢皮肤乳头瘤病可与假上皮瘤样和癌样改变相鉴别。局部淋巴运输受损似乎是这些乳头瘤发生发展的决定性触发机制。
