Niederauer H H, Schultz-Ehrenburg U, Tiedjen K U
Abteilung Allgemeine Dermatologie mit Schwerpunkt Histopathologie und Angiologie, Ruhr-Universität im St. Josef-Hospital Bochum.
Hautarzt. 1991 Aug;42(8):518-22.
The case of a patient with two plantar papillomatous tumours that had had a relapsing course over 10 years is presented. The tumours were located on the right forefoot and the left great toe. Several operations were performed for different diagnoses, i.e. plantar verrucae, verrucous carcinoma and pyoderma vegetans. Histologically, the papillomas proved to be pseudocarcinomatous hyperplasias with multiple ectatic dermal lymph plexuses. Indirect lymphography revealed a circumscribed lymphatic dysplasia with cystic-ectatic cutaneous vessels within the tumour area. Draining lymphatic collectors were conspicuously reduced in number. Isotope lymphography showed a normal lymph transport rate from the foot to the groin. It is concluded that the circumscribed disturbance of lymphatic drainage is the decisive cause of the reactive papillomatous hyperplasia. Thus, these papillomas clinically resembling verrucous carcinoma represent the tumour variant of a papillomatosis cutis lymphostatica.
本文介绍了一名患有两个足底乳头状瘤的患者病例，该病例病程长达10年且呈复发状态。肿瘤位于右前足和左大脚趾。因不同诊断（即跖疣、疣状癌和增殖性脓皮病）进行了多次手术。组织学检查显示，乳头状瘤为假癌性增生，伴有多个扩张的真皮淋巴丛。间接淋巴管造影显示肿瘤区域有局限性淋巴管发育异常，伴有囊性扩张的皮肤血管。引流淋巴管数量明显减少。同位素淋巴管造影显示从足部到腹股沟的淋巴转运速率正常。结论是，局限性淋巴引流障碍是反应性乳头状瘤样增生的决定性原因。因此，这些临床上类似疣状癌的乳头状瘤代表了皮肤淋巴性乳头状瘤病的肿瘤变体。
