Bratzke B, Orfanos C E
Universitäts-Hautklinik, Klinikum Steglitz, Freien Universität Berlin.
Hautarzt. 1988 Aug;39(8):514-8.
The case is reported of a 31-year-old homosexual male who developed distinct maculopapular and papulovesicular exanthema with aphthous-like, painful lesions of the oral mucosa, together with marked general symptoms (fever, diarrhoea, lymphadenopathy). This clinical picture suggested the primary acute phase of an initial HIV infection; during this phase the HIV-ELISA and Western blot test were negative. One year later the patient was found to be HIV-positive, showing oral candidosis, generalized lymphadenopathy, seborrhoeic eczema and zoster infection (L5/S1). A further year later, the patient developed full-blown AIDS with disseminated Kaposi's sarcoma. This observation underlines the acute inflammatory character of the primary phase of HIV infection with initial exanthema and documents the appearance of AIDS-associated Kaposi's sarcoma in a time period of maximally 2 years thereafter.
报告了一例31岁的同性恋男性病例，该患者出现明显的斑丘疹和丘疹水疱性皮疹，伴有口腔黏膜类似口疮样的疼痛性病变，同时伴有明显的全身症状（发热、腹泻、淋巴结病）。这种临床表现提示为初次HIV感染的原发性急性期；在此阶段，HIV-ELISA和Western印迹试验均为阴性。一年后，该患者被发现HIV阳性，表现为口腔念珠菌病、全身淋巴结病、脂溢性皮炎和带状疱疹感染（L5/S1）。再过一年，该患者发展为全面的艾滋病，伴有播散性卡波西肉瘤。这一观察结果强调了HIV感染原发性急性期伴有初始皮疹的急性炎症特征，并记录了此后最多2年内艾滋病相关卡波西肉瘤的出现。
