Dziekiewicz Marcin, Kowalska-Duplaga Kinga, Baranowska-Nowak Marta, Neścioruk Magdalena, Kuźniarski Stefan, Banasiuk Marcin, Banaszkiewicz Aleksandra
Department of Paediatric Gastroenterology and Nutrition, Medical University, Warsaw, Poland.
Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, Jagiellonian University, Kraków, Poland.
Ann Agric Environ Med. 2020 Mar 17;27(1):61-65. doi: 10.26444/aaem/105821. Epub 2019 Apr 8.
Inflammatory bowel disease (IBD) is long life disease that results from an interaction between a polygenetic predisposition and environmental factors, including smoking. The aim of this study was to evaluate beliefs about and awareness of smoking among adolescents with IBD compared to healthy controls.
Patients with IBD, Crohn's disease (CD) and ulcerative colitis (UC), and healthy controls were asked to complete a questionnaire on demographic data and smoking status. The questionnaire also included data on beliefs and awareness of smoking-related health effects, including effects on IBD.
A total of 139 IBD patients and 108 controls were enrolled in the study. Of the IBD patients, 17/139 (12.2%) were smokers compared to 18/108 (16.7%) of controls (p=0.3). Patients with IBD were nine times more likely to be everyday smokers than occasional smokers (OR=9.2, 95% CI: 1.9- 45.1, p=0.004). No difference was found between patients with CD and UC in their answers to the question of whether "smoking increases the risk for surgery in your type of IBD" (17/28 (60.7%) vs. 10/29 (34.5%), respectively (p=0.047). More patients with CD than UC were aware of the risks of smoking on their disease: extra-intestinal manifestations and disease exacerbation, OR=11.3 (95% CI: 4.1 - 30.9; p=0.000) and OR=19.3 (95% CI: 6.7 - 55.1; p=0.000), respectively.
The data obtained demonstrated that adolescents with CD are much more aware of the role of smoking on CD than are their peers with UC; however, this awareness is still unsatisfactory. Therefore, there is an unmet need to implement better anti-smoking strategies for this group of patients.
炎症性肠病（IBD）是一种由多基因易感性与环境因素（包括吸烟）相互作用导致的慢性疾病。本研究的目的是评估患有IBD的青少年与健康对照组相比，对吸烟的看法和认知。
IBD患者、克罗恩病（CD）患者、溃疡性结肠炎（UC）患者以及健康对照组被要求填写一份关于人口统计学数据和吸烟状况的问卷。该问卷还包括关于吸烟相关健康影响（包括对IBD的影响）的看法和认知数据。
本研究共纳入139例IBD患者和108例对照组。在IBD患者中，17/139（12.2%）为吸烟者，而对照组为18/108（16.7%）（p = 0.3）。IBD患者成为每日吸烟者的可能性是偶尔吸烟者的9倍（比值比=9.2，95%置信区间：1.9 - 45.1，p = 0.004）。在回答“吸烟是否会增加你这种类型的IBD手术风险”这一问题时，CD患者和UC患者之间未发现差异（分别为17/28（60.7%）和10/29（34.5%），p = 0.047）。知晓吸烟对其疾病（肠外表现和疾病加重）有风险的CD患者比UC患者更多，比值比分别为11.3（95%置信区间：4.1 - 30.9；p = 0.000）和19.3（95%置信区间：6.7 - 55.1；p = 0.000）。
所获得的数据表明，患有CD的青少年比患有UC的同龄人更清楚吸烟对CD的影响；然而，这种认知仍然不尽人意。因此，为这组患者实施更好的戒烟策略的需求尚未得到满足。
