Kály-Kullai K, Wittmann M, Noszticzius Z, Rosivall László
1Department of Physics, Group of Chemical Physics, Budapest University of Technology and Economics, Budapest, Hungary.
2Institute of Translational Medicine and International Nephrology Research and Training Center, Semmelweis University, Budapest, Hungary.
Physiol Int. 2020 Mar 1;107(1):1-11. doi: 10.1556/2060.2020.00015.
Viruses have caused many epidemics throughout human history. The novel coronavirus [10] is just the latest example. A new viral outbreak can be unpredictable, and development of specific defense tools and countermeasures against the new virus remains time-consuming even in today's era of modern medical science and technology. In the lack of effective and specific medication or vaccination, it would be desirable to have a nonspecific protocol or substance to render the virus inactive, a substance/protocol, which could be applied whenever a new viral outbreak occurs. This is especially important in cases when the emerging new virus is as infectious as SARS-CoV-2 [4].
In this editorial, we propose to consider the possibility of developing and implementing antiviral protocols by applying high purity aqueous chlorine dioxide (ClO2) solutions. The aim of this proposal is to initiate research that could lead to the introduction of practical and effective antiviral protocols. To this end, we first discuss some important properties of the ClO2 molecule, which make it an advantageous antiviral agent, then some earlier results of ClO2 gas application against viruses will be reviewed. Finally, we hypothesize on methods to control the spread of viral infections using aqueous ClO2 solutions.
在人类历史上，病毒引发了许多流行病。新型冠状病毒[10]就是最新的例子。新的病毒爆发可能无法预测，即使在当今现代医学科技时代，开发针对新病毒的特定防御工具和对策仍很耗时。在缺乏有效和特异性药物或疫苗的情况下，希望有一种非特异性方案或物质使病毒失活，这种物质/方案可在新的病毒爆发时随时应用。当出现像严重急性呼吸综合征冠状病毒2（SARS-CoV-2）[4]那样具有高度传染性的新病毒时，这一点尤为重要。
在这篇社论中，我们提议考虑通过应用高纯度二氧化氯（ClO2）水溶液来开发和实施抗病毒方案的可能性。这一提议的目的是启动相关研究，以引入切实有效的抗病毒方案。为此，我们首先讨论ClO2分子的一些重要特性，这些特性使其成为一种有利的抗病毒剂，然后回顾一些此前使用ClO2气体对抗病毒的结果。最后，我们对使用ClO2水溶液控制病毒感染传播的方法进行了假设。
