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对于急性原发性髌骨脱位,手术治疗是否比保守治疗能产生更好的效果?一项对10项随机对照试验的荟萃分析。

Does surgical treatment produce better outcomes than conservative treatment for acute primary patellar dislocations? A meta-analysis of 10 randomized controlled trials.

作者信息

Xing Xuewu, Shi Hongyu, Feng Shiqing

机构信息

Department of Orthopaedics, Tianjin First Central Hospital, First Central Clinical College of Tianjin Medical University, Tianjin, China.

Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

J Orthop Surg Res. 2020 Mar 24;15(1):118. doi: 10.1186/s13018-020-01634-5.

Abstract

PURPOSE

The objective of this study was to conduct the latest meta-analysis of randomized controlled trials (RCTs) that compare clinical results between surgery and conservative therapy of acute primary patellar dislocation (APPD), focusing on medial patellofemoral ligament (MPFL) reconstruction.

METHODS

We performed a literature search in Embase, The Cochrane Library, PubMed, and Medline to identify RCTs comparing APPD surgical treatment with conservative treatment from the establishment of each database to January 2019. The methodological quality of each RCT was assessed independently by the two authors through the Cochrane Collaboration's "Risk of Bias" tool. Mean differences of continuous variables and risk ratios of dichotomous variables were computed for the pooled data analyses. The I statistic and the χ test were used to evaluate heterogeneity, with the significance level set at I > 50% or P < 0.10.

RESULTS

Ten RCTs with a sum of 569 patients (297 receiving surgical treatment and 263 receiving conservative treatment) met the inclusion criteria for meta-analysis. Pooled data analysis showed no statistical difference in the field of subluxation rate, Kujala score, patient satisfaction, and frequency of reoperation between the two groups. Tegner activity score and recurrent dislocation rate in the conservative group were significantly higher than those in the surgically treated group.

CONCLUSIONS

Conservative treatment may produce better outcomes than surgery for APPD in consideration of Tegner activity score. However, in view of limited research available, the interpretation of the discoveries should be cautious. More convincing evidence is required to confirm the effect of MPFL reconstruction.

摘要

目的

本研究的目的是对随机对照试验(RCT)进行最新的荟萃分析,比较急性原发性髌骨脱位(APPD)手术治疗与保守治疗的临床结果,重点关注髌股内侧韧带(MPFL)重建。

方法

我们在Embase、Cochrane图书馆、PubMed和Medline中进行文献检索,以确定从每个数据库建立到2019年1月比较APPD手术治疗与保守治疗的RCT。两位作者通过Cochrane协作网的“偏倚风险”工具独立评估每个RCT的方法学质量。对汇总数据分析计算连续变量的平均差和二分变量的风险比。I统计量和χ检验用于评估异质性,显著性水平设定为I>50%或P<0.10。

结果

10项RCT共569例患者(297例接受手术治疗,263例接受保守治疗)符合荟萃分析的纳入标准。汇总数据分析显示,两组在半脱位率、Kujala评分、患者满意度和再次手术频率方面无统计学差异。保守治疗组的Tegner活动评分和复发性脱位率显著高于手术治疗组。

结论

考虑到Tegner活动评分,保守治疗可能比APPD手术治疗产生更好的结果。然而,鉴于现有研究有限,对这些发现的解释应谨慎。需要更有说服力的证据来证实MPFL重建的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96c9/7093955/07651719f4ba/13018_2020_1634_Fig1_HTML.jpg

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