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B型主动脉夹层胸主动脉腔内修复术后远端破口的选择性治疗策略的疗效

Outcomes of Selective Strategies for Distal Entry Tears After Thoracic Endovascular Aortic Repair in Type B Aortic Dissection.

作者信息

Fang Qing-Bo, Ci Hong-Bo, Ge Xiao-Hu

机构信息

Department of Vascular Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.

Department of Vascular Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.

出版信息

Ann Vasc Surg. 2020 Aug;67:316-321. doi: 10.1016/j.avsg.2020.03.007. Epub 2020 Mar 21.

Abstract

BACKGROUND

Distal entry tears have undesirable influence in type B aortic dissection (TBAD) after thoracic endovascular aortic repair (TEVAR), including inhibition of aortic remolding and increase of late aortic events. Therefore, distal entry tears should be managed. Nowadays, main strategies for managing distal entry tears included total and selective strategies. However, which strategy is better still remains controversial. The objective of the study is to investigate the outcomes of selective strategy for distal entry tears after TEVAR in TBAD.

METHODS

A total of 43 consecutive patients with TBAD with distal entry tears after TEVAR were administered with selective strategy for distal entry tears, including occlusion of the tear in the thoracic aortic segment, thrombosis of the reverse blood flow channel in the false lumen, and selective occlusion of distal entry tears. Mortality, complications, and aortic remolding in early follow-up (12 months after operation) were analyzed.

RESULTS

All 43 patients survived during the follow-up period. Operation was performed again for femoral artery reconstruction in 1 patient who had occlusion of the approach vessel during the follow-up period, and the remaining 42 patients had no uncomfortable symptoms and operation-related complications. The maximum diameter of the aorta was 32.03 ± 6.35 mm and 27.36 ± 4.92 mm, respectively, for before and after reintervention, and the difference was significant (t = 5.899, P < 0.001). The unthrombotic range of the false lumen after reintervention was significantly shrunken in all patients, compared with the range before reintervention.

CONCLUSIONS

Selective strategy was safe and effective, at least in early follow-up. Its effectiveness should be further verified by more clinical observation results and long-term follow-up results.

摘要

背景

在胸主动脉腔内修复术(TEVAR)治疗B型主动脉夹层(TBAD)后,远端破口对其有不良影响,包括抑制主动脉重塑和增加晚期主动脉事件。因此,远端破口需要处理。目前,处理远端破口的主要策略包括完全和选择性策略。然而,哪种策略更好仍存在争议。本研究的目的是探讨TEVAR治疗TBAD后远端破口的选择性策略的疗效。

方法

对43例TEVAR术后出现远端破口的连续性TBAD患者采用远端破口的选择性策略进行治疗,包括封堵胸主动脉段的破口、假腔逆向血流通道的血栓形成以及选择性封堵远端破口。分析早期随访(术后12个月)的死亡率、并发症和主动脉重塑情况。

结果

43例患者在随访期间均存活。1例患者在随访期间出现入路血管闭塞,再次行股动脉重建手术,其余42例患者无不适症状及手术相关并发症。再次干预前后主动脉最大直径分别为32.03±6.35mm和27.36±4.92mm,差异有统计学意义(t=5.899,P<0.001)。与再次干预前相比,所有患者再次干预后假腔未血栓形成的范围均明显缩小。

结论

选择性策略至少在早期随访中是安全有效的。其有效性有待更多临床观察结果和长期随访结果进一步验证。

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