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经动脉栓塞术用氰基丙烯酸正丁酯治疗腹壁出血。

Transarterial embolization with n-butyl cyanoacrylate for the treatment of abdominal wall hemorrhage.

机构信息

Division of Interventional Radiology, Department of Radiology, Hematology and Oncology, São Paulo University Ribeirão Preto School of Medicine, São Paulo, Brazil.

Division of Abdominal Radiology, Department of Radiology, Hematology and Oncology, São Paulo University Ribeirão Preto School of Medicine, São Paulo, Brazil.

出版信息

Diagn Interv Radiol. 2020 May;26(3):216-222. doi: 10.5152/dir.2019.19348.

Abstract

PURPOSE

We aimed to evaluate the effectiveness and safety of n-butyl cyanoacrylate (n-BCA) in the context of the transarterial embolization (TAE) of abdominal wall hemorrhage in an urgent scenario.

METHODS

A retrospective study of cases admitted from January 2008 to December 2017 in the emergency unit of our institution revealed 11 patients with abdominal wall hemorrhage who underwent digital subtraction angiography and TAE with n-BCA. We analyzed the sex, age, hemorrhagic risk factors, etiology, embolized vessel, technical success (no rebleeding in the embolized area), clinical success (hemoglobin level control and hemodynamic stability after the procedure), complications inherent to the procedure, and clinical outcome (mortality in 30 days).

RESULTS

The mean age was 63.4 years (52-83 years), with a predominance of the female sex (64%). The majority (91%) of patients presented hemorrhagic risk factors (chronic hepatopathy and anticoagulation drug usage). Spontaneous hemorrhage was present in 18% of patients, and the other 82% had an iatrogenic etiology. Technical success was achieved in 100% of the patients, which required the embolization of inferior epigastric artery in 10 patients (91%), circumflex iliac artery in 2 (18%), and superior epigastric artery in 1 (9%). Five patients were hemodynamically unstable, and despite achieving technical success, 4 (36%) died in less than 30 days due to decompensation of their clinical comorbidities caused by the acute phase. There were no complications inherent to the procedures.

CONCLUSION

The present study concludes that TAE with n-BCA is a safe and effective treatment for abdominal wall hemorrhage in an urgent scenario, with high rates of technical and clinical success.

摘要

目的

我们旨在评估在紧急情况下,经动脉栓塞术(TAE)中使用正丁基氰基丙烯酸酯(n-BCA)治疗腹壁出血的效果和安全性。

方法

回顾性分析了 2008 年 1 月至 2017 年 12 月期间在我院急诊收治的 11 例接受数字减影血管造影和 n-BCA 栓塞治疗的腹壁出血患者。我们分析了患者的性别、年龄、出血风险因素、病因、栓塞血管、技术成功(栓塞区域无再出血)、临床成功(血红蛋白水平控制和治疗后血流动力学稳定)、手术固有并发症和临床结局(30 天内死亡率)。

结果

患者的平均年龄为 63.4 岁(52-83 岁),女性占多数(64%)。大多数(91%)患者存在出血风险因素(慢性肝病和抗凝药物使用)。18%的患者为自发性出血,82%的患者为医源性病因。100%的患者达到了技术成功,需要栓塞 10 例(91%)患者的下腹部动脉、2 例(18%)患者的旋髂动脉和 1 例(9%)患者的上腹部动脉。5 例患者血流动力学不稳定,尽管达到了技术成功,但由于急性阶段其合并症的失代偿,4 例(36%)患者在 30 天内死亡。手术过程中无固有并发症。

结论

本研究表明,在紧急情况下,TAE 联合 n-BCA 治疗腹壁出血是一种安全有效的治疗方法,具有较高的技术和临床成功率。

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